Background The commonest cause of upper gastrointestinal symptoms is non‐ulcer
dyspepsia (NUD) and yet the pathophysiology of this condition has been poorly …

Background Functional dyspepsia (FD) is a relapsing and remitting condition affecting
between 5% and 10% of people. Efficacious therapies are available, but their relative …

Functional dyspepsia (FD) is a chronic upper gastrointestinal (GI) symptom complex that
routine diagnostic work-up, such as endoscopy, blood laboratory analysis, or radiological …

OBJECTIVES: Functional dyspepsia (FD) is a common condition in the general population;
however, its treatment remains a challenge. The aim of this study was to examine the …

Background: Functional dyspepsia (FD) is often treated with prokinetic agents; however, the
efficacy of prokinetic agents in patients with FD has been questioned recently. The aim of …

A variety of common and some not common gastrointestinal syndromes are thought to be
based on impaired gut motility. For some, the role of motility is well defined, for others and …

Abstract▴ Mosapride was effective in improving overall symptoms in patients with
gastrointestinal disorders, including chronic gastritis, gastro-oesophageal reflux disease and …

Aliment Pharmacol Ther 2012; 35: 175–182 Summary Background The mechanisms of the
development of symptoms in functional dyspepsia (FD) patients have not been fully …

Functional dyspepsia represents a heterogeneous group of gastrointestinal disorders
marked by the presence of upper abdominal pain or discomfort. Although its precise …

Abstract In the gut, serotonin (5-hydroxytryptamine: 5-HT) exerts a variety of effects on
intrinsic enteric neurons, extrinsic afferents, enterocytes and smooth muscle cells, which are …