Therapeutic strategies for enhancing angiogenesis in wound healing

AP Veith, K Henderson, A Spencer, AD Sligar… - Advanced drug delivery …, 2019 - Elsevier
The enhancement of wound healing has been a goal of medical practitioners for thousands
of years. The development of chronic, non-healing wounds is a persistent medical problem …

Poly (N-isopropylacrylamide)-based thermoresponsive surfaces provide new types of biomedical applications

K Nagase, M Yamato, H Kanazawa, T Okano - Biomaterials, 2018 - Elsevier
Thermoresponsive surfaces, prepared by grafting of poly (N-isopropylacrylamide)(PIPAAm)
or its copolymers, have been investigated for biomedical applications. Thermoresponsive …

3D printed complex tissue construct using stem cell-laden decellularized extracellular matrix bioinks for cardiac repair

J Jang, HJ Park, SW Kim, H Kim, JY Park, SJ Na… - Biomaterials, 2017 - Elsevier
Stem cell therapy is a promising therapeutic method for the treatment of ischemic heart
diseases; however, some challenges prohibit the efficacy after cell delivery due to hostile …

Human embryonic stem cell-derived cardiac progenitors for severe heart failure treatment: first clinical case report

P Menasché, V Vanneaux, A Hagège, A Bel… - European heart …, 2015 - academic.oup.com
Aims Comparative studies suggest that stem cells committed to a cardiac lineage are more
effective for improving heart function than those featuring an extra-cardiac phenotype. We …

Advances in the formation, use and understanding of multi-cellular spheroids

TM Achilli, J Meyer, JR Morgan - Expert opinion on biological …, 2012 - Taylor & Francis
Introduction: Developing in vitro models for studying cell biology and cell physiology is of
great importance to the fields of biotechnology, cancer research, drug discovery, toxicity …

Engineering cardiac muscle tissue: a maturating field of research

F Weinberger, I Mannhardt, T Eschenhagen - Circulation research, 2017 - Am Heart Assoc
Twenty years after the initial description of a tissue engineered construct, 3-dimensional
human cardiac tissues of different kinds are now generated routinely in many laboratories …

Cell sheet tissue engineering: cell sheet preparation, harvesting/manipulation, and transplantation

J Kobayashi, A Kikuchi, T Aoyagi… - Journal of biomedical …, 2019 - Wiley Online Library
Cell sheet tissue engineering is a concept for creating transplantable two‐dimensional (2D)
and three‐dimensional (3D) tissues and organs. This review describes three elements of …

Fabrication of functional three-dimensional tissues by stacking cell sheets in vitro

Y Haraguchi, T Shimizu, T Sasagawa, H Sekine… - Nature protocols, 2012 - nature.com
The fabrication of 3D tissues retaining the original functions of tissues/organs in vitro is
crucial for optimal tissue engineering and regenerative medicine. The fabrication of 3D …

Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction

R Guo, M Morimatsu, T Feng, F Lan, D Chang… - Stem Cell Research & …, 2020 - Springer
Stem cell-derived sheet engineering has been developed as the next-generation treatment
for myocardial infarction (MI) and offers attractive advantages in comparison with direct stem …

All roads lead to Rome (the heart): cell retention and outcomes from various delivery routes of cell therapy products to the heart

J Li, S Hu, D Zhu, K Huang, X Mei… - Journal of the …, 2021 - Am Heart Assoc
In the past decades, numerous preclinical studies and several clinical trials have evidenced
the feasibility of cell transplantation in treating heart diseases. Over the years, different …