The recent outbreak of the corona virus disease (COVID-19) has had major global impact.
The relationship between severe acute respiratory syndrome coronavirus (SARS-CoV-2) …

Fear, which can be expressed innately or after conditioning, is triggered when a danger or a
stimulus predicting immediate danger is perceived. Its role is to prepare the body to face this …

Dysregulated prefrontal control over amygdala is engaged in the pathogenesis of psychiatric
diseases including depression and anxiety disorders. Here we show that, in a rodent anxiety …

Depression and anxiety disorders are the two most prevalent psychiatric diseases that affect
hundreds of millions of individuals worldwide. Understanding the etiology and related …

Chronic stress is one of the most critical factors in the onset of depressive disorders; hence,
environmental factors such as psychosocial stress are commonly used to induce depressive …

Exercise is known to have beneficial effects on cognition, mood, and the brain. However,
exercise also activates the hypothalamic–pituitary–adrenal axis and increases levels of the …

Stress responses entail neuroendocrine, autonomic, and behavioral changes to promote
effective coping with real or perceived threats to one's safety. While these responses are …

Major depressive disorder (MDD) is associated with reduced concentrations of γ-
aminobutyric acid (GABA) that are normalized by antidepressant therapies. Moreover …

Background Chronic stress exposure increases the risk of developing various
neuropsychiatric illnesses. The behavioral sequelae of stress correlate with dendritic …

Oxidative and inflammatory signaling pathways have been identified as important targets for
mitigating hypoxic stress-induced neurological complications. Thus, the effects of …