Objective Inflammation plays a crucial role in the pathogenesis of mild cognitive impairment
(MCI) and Alzheimer's disease (AD). Our study aimed to analyse previous inconsistent …

Oxidative stress develops as a response to injury and reflects a breach in the cell's
antioxidant capacity. Therefore, the fine-tuning of reactive oxygen species (ROS) generation …

There is an increasing prevalence of Vascular Cognitive Impairment (VCI) worldwide, and
several studies have suggested that Chronic Cerebral Hypoperfusion (CCH) plays a critical …

This article gives a comprehensive overview of cytokine and other inflammation associated
protein levels in plasma, serum and cerebrospinal fluid (CSF) of patients with Alzheimer's …

The search for immune biomarkers in psychiatric disorders has primarily focused on pro-
inflammatory cytokines. Other immune proteins including chemokines have been relatively …

Low grade neuroinflammation has been suggested as one of the underlying mechanisms of
many psychiatric diseases as well as cognitive disorders. Interleukin 8 (IL-8), a …

Amyloid beta (Aβ) plays a major role in Alzheimer's disease (AD), and neuroinflammatory
processes mediated by Aβ plaque-induced microglial cells and astrocytes contribute to AD …

Objective Chemokines, which are chemotactic inflammatory mediators involved in
controlling the migration and residence of all immune cells, are closely associated with brain …

Immune activation and inflammation play significant roles in the pathogenesis of Alzheimer's
disease (AD). To test whether AD patients showed systemic manifestations of inflammation …

Neuroinflammation represents a central feature in the development of Alzheimer's disease
(AD). The resident innate immune cells of the brain are the principal players in …