Artemisinin and its derivatives are widely used throughout the world. The mechanism of
action of these compounds appears to involve the heme-mediated decomposition of the …

Improvement of quality of life and survival of cancer patients will be greatly enhanced by the
development of highly effective drugs to selectively kill malignant cells. Artemisinin and its …

Artemisinins are derived from extracts of sweet wormwood (Artemisia annua) and are well
established for the treatment of malaria, including highly drug-resistant strains. Their efficacy …

Since ancient times, humankind has had to struggle against the persistent onslaught of
pathogenic microorganisms. Nowadays, malaria is still the most important infectious disease …

Artemisinin derivatives are the most recent single drugs approved and introduced for public
antimalarial treatment. Although their recommended use is for treatment of Plasmodium …

As long as no effective malaria vaccine is available, chemotherapy belongs to the most
important weapons fighting malaria. One of the most promising new drug developments is …

The anti‑malarial drug artemisinin has shown anticancer activity in vitro and animal
experiments, but experience in human cancer is scarce. However, the ability of artemisinins …

The artemisinins are the most potent and rapidly acting antimalarial drugs. In response to
the global threat of multidrug-resistant malaria, they are now widely used in combination …

Background: Artemisinin is a chemical compound extracted from the wormwood plant,
Artemisia annua L. It has been shown to selectively kill cancer cells in vitro and retard the …

The artemisinin derivatives, dihydroartemisinin (DHA), artesunate, atemether and arteether,
are currently used for treatment of malaria in artemisinin combination therapies (ACT) with …