Lactational retrorsine exposure changes maternal milk components and disturbs metabolism homeostasis of offspring rats

Y Dai, Q Guo, K Xu, Z Gong, S Qiu, X Sun, J Liu… - Science of The Total …, 2023 - Elsevier
Pyrrolizidine alkaloids (PAs) are a type of plant-derived environmental toxins, which pose a
health hazard to human and livestock via contaminating soil, water, plants and food. In this …

Postpartum depression in rats causes poor maternal care and neurochemical alterations on dams and long-lasting impairment in sociability on the offspring

J Zaccarelli-Magalhães, GR Abreu… - Behavioural brain …, 2023 - Elsevier
Postpartum depression is a mentally disabling disease with multifactorial etiology that affects
women worldwide. It can also influence child development and lead to behavioral and …

Ketamine causes poor maternal care in rats with postpartum depression and leads to few behavioral and neurochemical alterations on male offspring

J Zaccarelli-Magalhães, GR Abreu… - Behavioural Brain …, 2024 - Elsevier
Ketamine is an anesthetic drug that also has antidepressant properties, with quick action.
Despite the great number of studies showing its effectiveness as a treatment for major …

Fluoxetine alters rat's milk properties causing impact on offspring's development

GR Abreu, J Zaccarelli-Magalhães, LS Féba… - Toxicology and Applied …, 2024 - Elsevier
Fluoxetine is an antidepressant used to treat several conditions including postpartum
depression. This disease causes cognitive, emotional, behavioral and physical changes …

[HTML][HTML] Prolonged exposure of rats to varenicline increases anxiety and alters serotonergic system, but has no effect on memory

J Zaccarelli-Magalhães, TM Sandini… - Pharmacology …, 2019 - Elsevier
Varenicline is a drug used for smoking addiction cessation treatment and acts as a partial
agonist of nicotinic cholinergic receptors. Recent clinical trial data support use of varenicline …

Perinatal exposure to an aromatase inhibitor glyphosate-base herbicide reduced male and female social behavior in juvenile age and the sexual behavior at adult …

EL Ricci, MO Ribeiro, AR Fukushima… - Brazilian Journal of …, 2022 - repositorio.usp.br
Objectives: The herbicide glyphosate, a pesticide used in agriculture to control weeds, both
in food crops and in other agricultural areas, has been identified as an endocrine modulator …

Prenatal exposure to integerrimine N-oxide enriched butanolic residue from Senecio brasiliensis affects behavior and striatal neurotransmitter levels of rats in …

TM Sandini, MSB Udo, TM Reis-Silva… - International Journal of …, 2015 - Elsevier
Pyrrolizidine alkaloids (PAs) are toxins that are exclusively biosynthesized by plants and are
commonly present in foods and herbs. PAs are usually associated with poisoning events in …

[HTML][HTML] Effects of the aqueous extract of Phyllanthus niruri Linn during pregnancy and lactation on neurobehavioral parameters of rats' offspring

M da Costa Alves, DE Pereira… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Phyllanthus niruri L.(Phyllanthaceae) is a plant used in
traditional medicine, mainly to treat kidney stones. However, the effects of maternal …

Perinatal glyphosate-based herbicide impaired maternal behavior by reducing the striatal dopaminergic activity and delayed the offspring reflex development

PRDA Rocha, MO Ribeiro, TM Sandini… - Atas de Saúde …, 2019 - repositorio.usp.br
O glifosato é um herbicida não seletivo, que causa mutagênese celular e efeitos tóxicos
embrionário, fetal e placentário, mesmo em baixas concentrações. Este estudo investigou …

Research progress of male reproductive toxicity of Chinese materia medicas

S Li, C Li, X Cheng, X Liu, M Han - … ‐Based Complementary and …, 2019 - Wiley Online Library
In recent years, as the infertility rate in China has been increasing year by year and semen
quality decreasing, male reproductive toxicity of drugs attracts more and more attention …