[HTML][HTML] Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism

Z Cui, X Zhao, FK Amevor, X Du, Y Wang, D Li… - Frontiers in …, 2022 - frontiersin.org
Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …

Neuropharmacological effects of quercetin: a literature-based review

MS Islam, C Quispe, R Hossain, MT Islam… - Frontiers in …, 2021 - frontiersin.org
Quercetin (QUR) is a natural bioactive flavonoid that has been lately very studied for its
beneficial properties in many pathologies. Its neuroprotective effects have been …

The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model …

AM Sabogal-Guáqueta, JI Munoz-Manco… - …, 2015 - Elsevier
Alzheimer's disease (AD) is the most common senile dementia in the world. Although
important progress has been made in understanding the pathogenesis of AD, current …

Life or death: neuroprotective and anticancer effects of quercetin

F Dajas - Journal of ethnopharmacology, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Quercetin is a ubiquitous flavonoid that is
present in numerous plants that are utilized in many different cultures for their nervous …

Polyphenols: multipotent therapeutic agents in neurodegenerative diseases

KS Bhullar, HPV Rupasinghe - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Aging leads to numerous transitions in brain physiology including synaptic dysfunction and
disturbances in cognition and memory. With a few clinically relevant drugs, a substantial …

Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions

N Suganthy, KP Devi, SF Nabavi, N Braidy… - Biomedicine & …, 2016 - Elsevier
Quercetin, a ubiquitous flavonoid that is widely distributed in plants is classified as a
cognitive enhancer in traditional and oriental medicine. The protective effects of quercetin for …

Habitual intake of dietary flavonoids and risk of Parkinson disease

X Gao, A Cassidy, MA Schwarzschild, EB Rimm… - Neurology, 2012 - AAN Enterprises
Objective: To prospectively examine whether higher intakes of total flavonoids and their
subclasses (flavanones, anthocyanins, flavan-3-ols, flavonols, flavones, and polymers) were …

Polyphenols in Parkinson's disease: a systematic review of in vivo studies

M Kujawska, J Jodynis-Liebert - Nutrients, 2018 - mdpi.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder.
However, therapeutic options treating only its symptoms are very disappointing. Therefore …

Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson's disease in rats

SS Karuppagounder, SK Madathil, M Pandey… - Neuroscience, 2013 - Elsevier
We tested quercetin, a dietary bioflavonoid with potent free radical scavenging action and
antioxidant activity, for its neuroprotective effects in rotenone-induced hemi-parkinsonian …

[HTML][HTML] Protective effect of hesperidin in a model of Parkinson's disease induced by 6-hydroxydopamine in aged mice

MS Antunes, ATR Goes, SP Boeira, M Prigol, CR Jesse - Nutrition, 2014 - Elsevier
Objective Parkinson's disease (PD) may be caused by the interaction of a number of factors,
including genetics, toxins, oxidative stress, mitochondrial abnormalities, and aging. Studies …