Machine learning and semantic analysis are computer-based methods to evaluate complex
relationships and predict future perspectives. We used these technologies to define recent …

Simple Summary Glycogen synthase kinase-3 beta is a protein kinase implicated in the
promotion and development of various cancers, including pancreatic cancer. In cell culture …

Purpose: Despite the significant association of molecular subtypes with poor prognosis in
patients with pancreatic ductal adenocarcinoma (PDAC), few efforts have been made to …

Extracellular vesicles (EVs) are small, lipid‐bilayer‐bound particles released by cells that
can contain important bioactive molecules, including lipids, RNAs, and proteins. Once …

Background Pancreatic adenocarcinoma (PDAC) is a devastating disease with an urgent
need for therapeutic innovation. Immune checkpoint inhibition has shown promise in a …

Pancreatic cancer has a dire prognosis and will represent the second leading cause of
cancer death in the next 10 years. The multifactorial approach represents one of the main …

A previously healthy man in his 60s was diagnosed with a rare histological subtype of
pancreatic cancer, adenosquamous carcinoma. After somatic mutation profiling, it was found …

Abstract Background The American Joint Committee on Cancer (AJCC) tumor‐node‐
metastasis (TNM) staging system focuses on traditional biological factors (BFs). The present …

Background: Immunotherapy has shown great success in various malignancies. However,
its efficacy in pancreatic ductal adenocarcinoma (PDAC) remains a challenge, and the lack …

Introduction: Pancreatic ductal adenocarcinoma (PDA) is an invasive cancer of the exocrine
pancreas with a 5-year survival rate (< 8%), highlighting the need for new therapies to …