Fluorine is a valuable probe for investigating the interactions of biological molecules
because of its favorable NMR characteristics, its small size, and its near total absence from …

There is a considerable current interest in understanding the function of antimicrobial
peptides for the development of potent novel antibiotic compounds with a very high …

Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were
used to examine the ultrastructural changes in bacteria induced by antimicrobial peptides …

Abstract PGLa and magainin 2 (MAG2) are amphiphilic α-helical membranolytic peptides
from frog skin with known synergistic antimicrobial activity. By systematically mutating …

There is some overlap in the biological activities of cell-penetrating peptides (CPPs) and
antimicrobial peptides (AMPs). We compared nine AMPs, seven CPPs, and a fusion peptide …

Amyloid formation, a complex process involving many intermediate states, is proposed to be
the driving force for amyloid-related toxicity in common degenerative diseases …

The membrane alignment of the amphiphilic α-helical model peptide MSI-103 (sequence
[KIAGKIA] 3-NH2) was examined by solid state 2H-NMR in different lipid systems by …

Membrane-active antimicrobial peptides (AMPs) are challenging to study experimentally, but
relatively easy to investigate using molecular dynamics (MD) computer simulations. For this …

Membrane thinning has been discussed as a fundamental mechanism by which
antimicrobial peptides can perturb cellular membranes. To understand which factors play a …

How can highly charged, cationic antimicrobial peptides (AMPs) translocate across
hydrophobic lipid bilayers despite the prohibitive energetic penalty to do so? A common …