Tigerstedt and Bergman discovered and named renin in 1898. In the opening paragraph of
their paper they drew attention to Brown-S£ quard's (1893) theory that various organs of the …

The peripheral and central effects of some non-steroid anti-inflammatory drugs, aspirin,
indomethacin, paracetamol and phenacetin were studied by comparing their intraplantar …

Publisher Summary This chapter reviews substantial anatomical data describing the
distribution of bradykinin (BK) receptors as well as that of the biochemical machinery for the …

The object of this chapter is to review the effects of capsaicin-like pungent agents, with
special attention to the unique, irreversible impairment in thermoregulation induced by these …

The objective of this study was to investigate the site of action of dipyrone in rat paw
prostaglandininduced hyperalgesia. The intracerebroventricular (icv) injection of dipyrone …

Bradykinin-like immunoreactive structures were localized in rat brain by the indirect
immunofluorescence method. Specificity of staining was demonstrated by:(i) the absence of …

A monoclonal antibody against purified rat urinary kallikrein was coupled to agarose and
used to isolate kallikrein from rat brain. The purified enzyme has N alpha-tosyl-L-arginine …

The analgesic activities of intracerebroventricular (icy) administrations of some analgesic
drugs, morphine, indomethacin, diclofenac, aminopyrine and acetaminophen, were studied …

Bradykinin and related kinins are potent vasodilators. Inhibition of peripheral vascular
smooth-muscle tone may result from the actions of kinins at different levels. These include …

In conscious spontaneously hypertensive rats, intraxerebroventricular injection of captopril
(2 mg/kg) resulted in a rapid hypotensive response that lasted several hours. The same …