[HTML][HTML] The overlap between vascular disease and Alzheimer's disease-lessons from pathology

J Attems, KA Jellinger - BMC medicine, 2014 - Springer
Recent epidemiological and clinico-pathological data indicate considerable overlap
between cerebrovascular disease (CVD) and Alzheimer's disease (AD) and suggest …

Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup

RA Sperling, CR Jack Jr, SE Black, MP Frosch… - Alzheimer's & …, 2011 - Elsevier
Amyloid imaging related abnormalities (ARIA) have now been reported in clinical trials with
multiple therapeutic avenues to lower amyloid-β burden in Alzheimer's disease (AD). In …

Intracerebral haemorrhage

AI Qureshi, AD Mendelow, DF Hanley - The Lancet, 2009 - thelancet.com
Intracerebral haemorrhage is an important public health problem leading to high rates of
death and disability in adults. Although the number of hospital admissions for intracerebral …

Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum

A Charidimou, Q Gang, DJ Werring - Journal of Neurology …, 2012 - jnnp.bmj.com
Sporadic cerebral amyloid angiopathy (CAA) is a common age related cerebral small vessel
disease, characterised by progressive deposition of amyloid-β (Aβ) in the wall of small to …

[HTML][HTML] Pathology and pathogenesis of vascular cognitive impairment—a critical update

KA Jellinger - Frontiers in aging neuroscience, 2013 - frontiersin.org
Vascular cognitive impairment (VCI)[vascular cognitive disorder (VCD), vascular dementia]
describes a continuum of cognitive disorders ranging from mild cognitive impairment (MCI) …

Cerebral white matter: neuroanatomy, clinical neurology, and neurobehavioral correlates

JD Schmahmann, EE Smith, FS Eichler… - Annals of the New …, 2008 - Wiley Online Library
Lesions of the cerebral white matter (WM) result in focal neurobehavioral syndromes,
neuropsychiatric phenomena, and dementia. The cerebral WM contains fiber pathways that …

MR imaging detection of cerebral microbleeds: effect of susceptibility-weighted imaging, section thickness, and field strength

RNK Nandigam, A Viswanathan… - American Journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The emergence of cerebral microbleeds (CMB) as
common MR imaging findings raises the question of how MR imaging parameters influence …

[HTML][HTML] Cerebral microbleeds: a review of clinical, genetic, and neuroimaging associations

PA Yates, VL Villemagne, KA Ellis… - Frontiers in …, 2014 - frontiersin.org
Cerebral microbleeds (microbleeds) are small, punctuate hypointense lesions seen in T2*
Gradient-Recall Echo (GRE) and Susceptibility-Weighted (SWI) Magnetic Resonance …

Incidence of cerebral microbleeds in the general population: the Rotterdam Scan Study

MMF Poels, MA Ikram, A van der Lugt, A Hofman… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Cerebral microbleeds are frequently seen in the general elderly
population, but it is unknown at what rate they occur with aging and whether once present …

[HTML][HTML] Cerebral hypoperfusion accelerates cerebral amyloid angiopathy and promotes cortical microinfarcts

Y Okamoto, T Yamamoto, RN Kalaria, H Senzaki… - Acta …, 2012 - Springer
Cortical microinfarcts (CMIs) observed in brains of patients with Alzheimer's disease tend to
be located close to vessels afflicted with cerebral amyloid angiopathy (CAA). CMIs in …