Advances in the development of delivery, repair, and specificity strategies for the CRISPR-
Cas9 genome engineering toolbox are helping researchers understand gene function with …

Antibodies are among the most frequently used tools in basic science research and in
clinical assays, but there are no universally accepted guidelines or standardized methods …

This unit provides an overview of DNA microarrays. Microarrays are a technology in which
thousands of nucleic acids are bound to a surface and are used to measure the relative …

The future of biocuration | Nature Skip to main content Thank you for visiting nature.com. You
are using a browser version with limited support for CSS. To obtain the best experience, we …

Immunotherapies have emerged as one of the most promising approaches to treat patients
with cancer. Recently, there have been many clinical successes using checkpoint receptor …

Promoting coherent minimum reporting guidelines for biological and biomedical investigations:
the MIBBI project | Nature Biotechnology Skip to main content Thank you for visiting …

Objective To assess whether the completeness of reporting of health research is related to
journals' endorsement of reporting guidelines. Design Systematic review. Data sources …

Less than 1% of published cancer biomarkers actually enter clinical practice. Although best
practices for biomarker development are published, optimistic investigators may not …

Rationale Autism spectrum disorder (ASD) is a complex heterogeneous
neurodevelopmental disorder with onset during early childhood and typically a life-long …

Background: Expression levels of mRNA and protein by cell types exhibit a range of
correlations for different genes. In this study, we compared levels of mRNA abundance for …