Mechanistic insight for improving butenyl-spinosyn production through combined ARTP/UV mutagenesis and ribosome engineering in Saccharopolyspora pogona

X Zhao, MH Hussain, A Mohsin, Z Liu, Z Xu… - … in Bioengineering and …, 2024 - frontiersin.org
Butenyl-spinosyn is a highly effective, wide-spectrum and environmentally-friendly biological
insecticide produced by Saccharopolyspora pogona. However, its scale-up is impeded due …

Insights into the mechanism of mycelium transformation of Streptomyces toxytricini into pellet

P Kumar, D Rajput, KK Dubey - FEMS microbes, 2023 - academic.oup.com
Formation of the mycelial pellet in submerged cultivation of Streptomycetes is unwanted in
industrial fermentation processes as it imposes mass transfer limitations, changes in the …

Combinatorial strain improvement and bioprocess development for efficient production of ε-poly-L-lysine in Streptomyces albulus

D Zhu, Y Liu, H Yang, J Zhang, G Zheng, H Zhang… - Bioresource …, 2024 - Elsevier
Abstract ε-Poly-L-lysine (ε-PL) is an amino acid homopolymer with diverse potential
applications in the food, pharmaceutical and cosmetic industries. To improve its …

Development of a native-locus dual reporter system for the efficient screening of the hyper-production of natural products in Streptomyces

JY Zhou, BB Ma, QW Zhao, XM Mao - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Streptomyces is renowned for its abundant production of bioactive secondary metabolites,
but most of these natural products are produced in low yields. Traditional rational network …

MULTI-STEPS MICROFILTRATION OF MICELLES FROM FERMENTATION OF Streptomyces tsukubaensis AND ITS IMPACT ON PROTEINS RETENTION AND …

AS Bertan, MA Cremasco - Food and Bioproducts Processing, 2024 - Elsevier
This study reports the application of microfiltration Streptomyces tsukubaensis micelles from
fermentation broths, for tacrolimus recovery, investigating the use of a new multi-step …