Peptide design principles for antimicrobial applications
The increased incidence of bacterial resistance to available antibiotics represents a major
global health problem and highlights the need for novel anti-infective therapies …
global health problem and highlights the need for novel anti-infective therapies …
Synthetic biology and computer-based frameworks for antimicrobial peptide discovery
Antibiotic resistance is one of the greatest challenges of our time. This global health problem
originated from a paucity of truly effective antibiotic classes and an increased incidence of …
originated from a paucity of truly effective antibiotic classes and an increased incidence of …
Rational design of stapled antimicrobial peptides
YH You, HY Liu, YZ Zhu, H Zheng - Amino Acids, 2023 - Springer
The global increase in antimicrobial drug resistance has dramatically reduced the
effectiveness of traditional antibiotics. Structurally diverse antibiotics are urgently needed to …
effectiveness of traditional antibiotics. Structurally diverse antibiotics are urgently needed to …
Reprogramming biological peptides to combat infectious diseases
MDT Torres, C de la Fuente-Nunez - Chemical Communications, 2019 - pubs.rsc.org
With the rapid spread of resistance among parasites and bacterial pathogens, antibiotic-
resistant infections have drawn much attention worldwide. Consequently, there is an urgent …
resistant infections have drawn much attention worldwide. Consequently, there is an urgent …
Virtual screening for SARS-CoV-2 main protease inhibitory peptides from the putative hydrolyzed peptidome of rice bran
N Harnkit, T Khongsonthi, N Masuwan, P Prasartkul… - Antibiotics, 2022 - mdpi.com
The Coronavirus Disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has led to the loss of life and has affected the life …
syndrome coronavirus 2 (SARS-CoV-2) has led to the loss of life and has affected the life …
iAMAP-SCM: a novel computational tool for large-scale identification of antimalarial peptides using estimated propensity scores of dipeptides
Antimalarial peptides (AMAPs) varying in length, amino acid composition, charge,
conformational structure, hydrophobicity, and amphipathicity reflect their diversity in …
conformational structure, hydrophobicity, and amphipathicity reflect their diversity in …
Natural and redesigned wasp venom peptides with selective antitumoral activity
MDT Torres, GP Andrade, RH Sato… - Beilstein Journal of …, 2018 - beilstein-journals.org
About 1 in 8 US women (≈ 12%) will develop invasive breast cancer over the course of their
lifetime. Surgery, chemotherapy, radiotherapy, and hormone manipulation constitute the …
lifetime. Surgery, chemotherapy, radiotherapy, and hormone manipulation constitute the …
The effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1
Antimicrobial peptides (AMPs) are biologically active molecules with a broad-spectrum
activity against a myriad of microorganisms. Aside from their antimicrobial functions, AMPs …
activity against a myriad of microorganisms. Aside from their antimicrobial functions, AMPs …
The wasp venom antimicrobial peptide polybia‐CP and its synthetic derivatives display antiplasmodial and anticancer properties
The wasp venom‐derived antimicrobial peptide polybia‐CP has been previously shown to
exhibit potent antimicrobial activity, but it is also highly toxic. Previously, using a …
exhibit potent antimicrobial activity, but it is also highly toxic. Previously, using a …
Angiotensin II-derived constrained peptides with antiplasmodial activity and suppressed vasoconstriction
Abstract Angiotensin II (Ang II) is a natural mammalian hormone that has been described to
exhibit antiplasmodial activity therefore constituting a promising alternative for the treatment …
exhibit antiplasmodial activity therefore constituting a promising alternative for the treatment …