Ebola virus disease
ST Jacob, I Crozier, WA Fischer, A Hewlett… - Nature reviews Disease …, 2020 - nature.com
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …
Pattern recognition and signaling mechanisms of RIG-I and MDA5
Most organisms rely on innate immune receptors to recognize conserved molecular
structures from invading microbes. Two essential innate immune receptors, RIG-I and MDA5 …
structures from invading microbes. Two essential innate immune receptors, RIG-I and MDA5 …
Filovirus pathogenesis and immune evasion: insights from Ebola virus and Marburg virus
I Messaoudi, GK Amarasinghe, CF Basler - Nature Reviews …, 2015 - nature.com
Ebola viruses and Marburg viruses, members of the filovirus family, are zoonotic pathogens
that cause severe disease in people, as highlighted by the latest Ebola virus epidemic in …
that cause severe disease in people, as highlighted by the latest Ebola virus epidemic in …
Structure of the Ebola virus polymerase complex
B Yuan, Q Peng, J Cheng, M Wang, J Zhong, J Qi… - Nature, 2022 - nature.com
Filoviruses, including Ebola virus, pose an increasing threat to the public health. Although
two therapeutic monoclonal antibodies have been approved to treat the Ebola virus …
two therapeutic monoclonal antibodies have been approved to treat the Ebola virus …
Innate immune responses to acute viral infection during pregnancy
EF Cornish, I Filipovic, F Åsenius, DJ Williams… - Frontiers in …, 2020 - frontiersin.org
Immunological adaptations in pregnancy allow maternal tolerance of the semi-allogeneic
fetus but also increase maternal susceptibility to infection. At implantation, the endometrial …
fetus but also increase maternal susceptibility to infection. At implantation, the endometrial …
Structure and assembly of the Ebola virus nucleocapsid
W Wan, L Kolesnikova, M Clarke, A Koehler, T Noda… - Nature, 2017 - nature.com
Ebola and Marburg viruses are filoviruses: filamentous, enveloped viruses that cause
haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes …
haemorrhagic fever. Filoviruses are within the order Mononegavirales, which also includes …
[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …
Unexpected inheritance: multiple integrations of ancient bornavirus and ebolavirus/marburgvirus sequences in vertebrate genomes
VA Belyi, AJ Levine, AM Skalka - PLoS pathogens, 2010 - journals.plos.org
Vertebrate genomes contain numerous copies of retroviral sequences, acquired over the
course of evolution. Until recently they were thought to be the only type of RNA viruses to be …
course of evolution. Until recently they were thought to be the only type of RNA viruses to be …
Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3′ to 5′ exonuclease activity essential for immune suppression
KM Hastie, CR Kimberlin… - Proceedings of the …, 2011 - National Acad Sciences
Lassa fever virus, a member of the family Arenaviridae, is a highly endemic category A
pathogen that causes 300,000–500,000 infections per year in Western Africa. The arenaviral …
pathogen that causes 300,000–500,000 infections per year in Western Africa. The arenaviral …
Protein interaction mapping identifies RBBP6 as a negative regulator of Ebola virus replication
Ebola virus (EBOV) infection often results in fatal illness in humans, yet little is known about
how EBOV usurps host pathways during infection. To address this, we used affinity tag …
how EBOV usurps host pathways during infection. To address this, we used affinity tag …