Chimeric antigen receptor (CAR)-engineered T cells (CAR-T cells) have yielded
unprecedented efficacy in B cell malignancies, most remarkably in anti-CD19 CAR-T cells …

Cancer nanotheranostics aims to combine imaging and therapy of cancer through use of
nanotechnology. The ability to engineer nanomaterials to interact with cancer cells at the …

Cancer stem cells (CSCs) represent a rare population of cells with the capacity to self-renew
and give rise to heterogeneous cell lineages within a tumour. Whilst the mechanisms …

Cancer stem cells (CSCs) represent a subpopulation of tumor cells that possess self‐
renewal and tumor initiation capacity and the ability to give rise to the heterogenous …

The relationships between cancer and stemness have a long history that is traced here.
From the mid‐19th century when the first theory on the embryonic origin of cancer was …

Epithelial–mesenchymal transition (EMT) is defined by the loss of epithelial characteristics
and the acquisition of a mesenchymal phenotype. In this process, cells acquire molecular …

To achieve deep tumor penetration of large‐sized nanoparticles (NPs), we have developed
a reversible swelling–shrinking nanogel in response to pH variation for a sequential intra …

Background Cancer stem cells (CSCs) can proliferate and self-renew extensively due to
their ability to express anti-apoptotic and drug resistant proteins, thus sustaining tumor …

Cancer stem cells (CSCs) are thought to drive tumor growth, metastasis and
chemoresistance. Although surface markers such as CD133 and CD44 have been …

Cancer stem cells (CSCs) are a sub-population of cells within cancer tissues with tumor
initiation, drug resistance and metastasis properties. CSCs also have been considered as …