Epithelial‐to‐mesenchymal transition in oral squamous cell carcinoma: challenges and opportunities

Z Ling, B Cheng, X Tao - International journal of cancer, 2021 - Wiley Online Library
Oral squamous cell carcinoma (OSCC) is the most common malignancy representing 90%
of all forms of oral cancer worldwide. Although great efforts have been made in the past …

Potential Immunohistochemical Biomarkers for Grading Oral Dysplasia: A Literature Review

J Zdrojewski, M Nowak, K Nijakowski, J Jankowski… - Biomedicines, 2024 - mdpi.com
Oral cancer is a prevalent global health issue, with significant morbidity and mortality rates.
Despite available preventive measures, it remains one of the most common cancers …

Cyclin D1 in oral premalignant lesions and oral squamous cell carcinoma: An immunohistochemical study

RB Moharil, S Khandekar, A Dive… - Journal of Oral and …, 2020 - journals.lww.com
Background: Cyclin D1 is derived from PRAD1 or CCND1 gene located on chromosome
11q13 and it acts as a positive regulator of the cell cycle. In normal cells, cyclin D1 promotes …

CDK4, CDK6, cyclin D1 and Notch1 immunocytochemical expression of oral brush liquid‐based cytology for the diagnosis of oral leukoplakia and oral cancer

O Kujan, G Huang, A Ravindran… - Journal of Oral …, 2019 - Wiley Online Library
Objectives This study aimed to investigate the feasibility of using oral liquid‐based brush
cytology (OLBC) coupled with immunocytochemistry as a minimally invasive approach to …

[HTML][HTML] Prognostic role of epithelial-mesenchymal transition markers “E-Cadherin, β-Catenin, ZEB1, ZEB2 and p63” in bladder carcinoma

RA Moussa, AI Ali - World Journal of Oncology, 2019 - ncbi.nlm.nih.gov
Background This study aimed to investigate the expression of epithelial-mesenchymal
markers' E-cadherin, β-catenin, zinc-finger E-box-binding homeobox 1 (ZEB1), zinc-finger E …

Prediction of lymphovascular and perineural invasion of oral squamous cell carcinoma by combined expression of p63 and Cyclin D1

NH Al-Rawi, S Al Kawas, M Al Ani… - European Journal of …, 2023 - thieme-connect.com
Objectives The aim of this study was to determine the value of immune expression of p63
and cyclin D1 in the prediction of lymphovascular invasion (LVI) and perineural invasion …

Immunohistochemical evaluation of cyclin D1 and p63 in odontogenic keratocyst and unicystic ameloblastoma

E Escobar, F Gómez-Valenzuela, C Peñafiel… - Revista Española de …, 2024 - Elsevier
Introduction Odontogenic keratocyst (OKC) and unicystic ameloblastoma (UA) are lesions of
odontogenic origin. Both lesions are morphologically cysts. However, they are classified as …

Differential expression of potential biomarkers of oral squamous cell carcinoma development

PF Pansini, IB do Valle, TCD Damasceno… - Head and Neck …, 2021 - Springer
To evaluate molecular epithelial changes, we investigated whether a profile of survivin,
cyclin dependent kinase inhibitor 2A (CDKN2A), epidermal growth factor receptor (EGFR) …

Cyclin D1 and P27KIP1: the gatekeepers of dysplasia

MM Bakr, S Guan, N Firth… - Journal of …, 2018 - immunologyresearchjournal.com
There is increasing evidence suggesting that cyclins, cyclin-dependent kinases (CDKs), and
cyclin-dependent kinase inhibitors (CDIs) either are themselves targets for genetic change …

Immunohistochemical expression and evaluation of cyclin D1 and minichromosome maintenance 2 in oral squamous cell carcinoma and verrucous carcinoma

TR Menaka, SS Ravikumar, K Dhivya… - Journal of Oral and …, 2022 - journals.lww.com
Background: The study of cell proliferation is important for assessing the tumor behavior,
prognosis and patient survival of oral carcinomas. As literature search did not reveal …