BACKGROUND: Liver biopsy is the reference standard for diagnosing the extent of fibrosis
in chronic liver disease; however, it is invasive, with the potential for serious complications …

Chronic hepatitis B (CHB) is one of the most widespread liver diseases in the world. It is
currently incurable and can lead to liver cirrhosis and cancer. The considerable impacts on …

A growing number of jurisdictions now request economic data in support of their decision-
making procedures for the pricing and/or reimbursement of health technologies. Because …

Background & Aims Chronic liver (CLD) is a major public health concern. We assessed its
effects on quality of life and work productivity, as well as its economic burden in the United …

Ultrasonography (US) is generally recommended for the surveillance of hepatocellular
carcinoma (HCC) in patients at risk. However, in patients with cirrhosis who have sufficiently …

Background Despite the high burden of hepatitis B virus (HBV) infection in sub-Saharan
Africa, absence of widespread screening and poor access to treatment leads to most people …

BACKGROUND & AIMS: Persons with chronic hepatitis B virus (HBV) infection are at risk of
developing cirrhosis and hepatocellular carcinoma. Early detection of chronic HBV infection …

Objective The cost-effectiveness of antiviral treatment in adult immune-tolerant (IT) phase
chronic hepatitis B (CHB) patients is uncertain. Design We designed a Markov model to …

Background Within the framework of economic evaluations, the transferability of utility scores
between jurisdictions remains unclear. The EQ-5D is a generic instrument for measuring …

Abstract (See the editorial commentary by Lo Re III, on pages 1307–1309.) Background.
Hepatitis B virus (HBV) continues to cause significant morbidity and mortality in the United …