C Lu, RH Wijffels, VAP Martins dos Santos… - Microbial …, 2024 - Wiley Online Library
Medium‐chain‐length α, ω‐diols (mcl‐diols) play an important role in polymer production, traditionally depending on energy‐intensive chemical processes. Microbial cell factories …
G Favoino, N Krink, T Schwanemann… - Microbial …, 2024 - Wiley Online Library
Malonyl‐coenzyme A (CoA) is a key precursor for the biosynthesis of multiple value‐added compounds by microbial cell factories, including polyketides, carboxylic acids, biofuels, and …
White-rot fungi (WRF) are the most efficient lignin-degrading organisms in nature. However, their capacity to use lignin-related aromatic compounds, such as 4-hydroxybenzoate, as …
Pseudomonas putida KT2440 is a robust, aromatic catabolic bacterium that has been widely engineered to convert bio-based and waste-based feedstocks to target products. Towards …
T Schwanemann, M Otto, B Wynands… - Metabolic …, 2023 - Elsevier
Malonyl-CoA is a central precursor for biosynthesis of a wide range of complex secondary metabolites. The development of platform strains with increased malonyl-CoA supply can …
Q Yu, L Sun, F Peng, C Sun, F Xiong, M Sun, J Liu… - Microorganisms, 2023 - mdpi.com
The abnormal proliferation of Cutibacterium acnes is the main cause of acne vulgaris. Natural antibacterial plant extracts have gained great interest due to the efficacy and safety …
Q Guo, J Su, Y Liao, Y Yu, L Luo, X Weng… - Applied and …, 2024 - Am Soc Microbiol
The last step of the initiation phase of fatty acid biosynthesis in most bacteria is catalyzed by the 3-ketoacyl-acyl carrier protein (ACP) synthase III (FabH). Pseudomonas syringae pv …
T Yang, G Li, Y Xu, X He, B Song, Y Cao - BMC microbiology, 2024 - Springer
Background Polycystic ovary syndrome (PCOS) is an endocrinopathy in childbearing-age females which can cause many complications, such as diabetes, obesity, and dyslipidemia …
Q Guo, C Zhong, H Dong, JE Cronan… - Journal of Biological …, 2024 - ASBMB
The condensation of acetyl-CoA with malonyl-acyl carrier protein (ACP) by β-ketoacyl-ACP synthase III (KAS III, FabH) and decarboxylation of malonyl-ACP by malonyl-ACP …