Elastomeric vitrimers from designer polyhydroxyalkanoates with recyclability and biodegradability

RM Cywar, C Ling, RW Clarke, DH Kim… - Science …, 2023 - science.org
Cross-linked elastomers are stretchable materials that typically are not recyclable or
biodegradable. Medium-chain-length polyhydroxyalkanoates (mcl-PHAs) are soft and …

Pseudomonas putida as a platform for medium‐chain length α,ω‐diol production: Opportunities and challenges

C Lu, RH Wijffels, VAP Martins dos Santos… - Microbial …, 2024 - Wiley Online Library
Medium‐chain‐length α, ω‐diols (mcl‐diols) play an important role in polymer production,
traditionally depending on energy‐intensive chemical processes. Microbial cell factories …

Enhanced biosynthesis of poly(3‐hydroxybutyrate) in engineered strains of Pseudomonas putida via increased malonyl‐CoA availability

G Favoino, N Krink, T Schwanemann… - Microbial …, 2024 - Wiley Online Library
Malonyl‐coenzyme A (CoA) is a key precursor for the biosynthesis of multiple value‐added
compounds by microbial cell factories, including polyketides, carboxylic acids, biofuels, and …

Biochemical and structural characterization of enzymes in the 4-hydroxybenzoate catabolic pathway of lignin-degrading white-rot fungi

E Kuatsjah, A Schwartz, M Zahn, K Tornesakis… - Cell Reports, 2024 - cell.com
White-rot fungi (WRF) are the most efficient lignin-degrading organisms in nature. However,
their capacity to use lignin-related aromatic compounds, such as 4-hydroxybenzoate, as …

[HTML][HTML] Comparison of wild-type KT2440 and genome-reduced EM42 Pseudomonas putida strains for muconate production from aromatic compounds and glucose

CR Amendola, WT Cordell, CM Kneucker… - Metabolic …, 2024 - Elsevier
Pseudomonas putida KT2440 is a robust, aromatic catabolic bacterium that has been widely
engineered to convert bio-based and waste-based feedstocks to target products. Towards …

A Pseudomonas taiwanensis Malonyl-CoA platform strain for polyketide synthesis

T Schwanemann, M Otto, B Wynands… - Metabolic …, 2023 - Elsevier
Malonyl-CoA is a central precursor for biosynthesis of a wide range of complex secondary
metabolites. The development of platform strains with increased malonyl-CoA supply can …

Antimicrobial Activity of Stilbenes from Bletilla striata against Cutibacterium acnes and Its Effect on Cell Membrane

Q Yu, L Sun, F Peng, C Sun, F Xiong, M Sun, J Liu… - Microorganisms, 2023 - mdpi.com
The abnormal proliferation of Cutibacterium acnes is the main cause of acne vulgaris.
Natural antibacterial plant extracts have gained great interest due to the efficacy and safety …

An atypical 3-ketoacyl ACP synthase III required for acyl homoserine lactone synthesis in Pseudomonas syringae pv. syringae B728a

Q Guo, J Su, Y Liao, Y Yu, L Luo, X Weng… - Applied and …, 2024 - Am Soc Microbiol
The last step of the initiation phase of fatty acid biosynthesis in most bacteria is catalyzed by
the 3-ketoacyl-acyl carrier protein (ACP) synthase III (FabH). Pseudomonas syringae pv …

Characterization of the gut microbiota in polycystic ovary syndrome with dyslipidemia

T Yang, G Li, Y Xu, X He, B Song, Y Cao - BMC microbiology, 2024 - Springer
Background Polycystic ovary syndrome (PCOS) is an endocrinopathy in childbearing-age
females which can cause many complications, such as diabetes, obesity, and dyslipidemia …

Diversity in fatty acid elongation enzymes: The FabB long-chain β-ketoacyl-ACP synthase I initiates fatty acid synthesis in Pseudomonas putida F1

Q Guo, C Zhong, H Dong, JE Cronan… - Journal of Biological …, 2024 - ASBMB
The condensation of acetyl-CoA with malonyl-acyl carrier protein (ACP) by β-ketoacyl-ACP
synthase III (KAS III, FabH) and decarboxylation of malonyl-ACP by malonyl-ACP …