Cerebrovascular reactivity (CVR) MRI with CO2 challenge: a technical review

P Liu, B Jill, H Lu - Neuroimage, 2019 - Elsevier
Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular reserve and provides
important information about vascular health in a range of brain conditions and diseases …

Vascular and neural basis of the BOLD signal

PJ Drew - Current opinion in neurobiology, 2019 - Elsevier
Highlights•The architecture of the cerebral vasculature sculpts the hemodynamics
response.•The BOLD signal is correlated with increases in gamma-band power in the LFP …

Emerging roles of microfluidics in brain research: from cerebral fluids manipulation to brain-on-a-chip and neuroelectronic devices engineering

J Wan, S Zhou, HJ Mea, Y Guo, H Ku… - Chemical …, 2022 - ACS Publications
Remarkable progress made in the past few decades in brain research enables the
manipulation of neuronal activity in single neurons and neural circuits and thus allows the …

BOLD signal physiology: models and applications

CJ Gauthier, AP Fan - Neuroimage, 2019 - Elsevier
The BOLD contrast mechanism has a complex relationship with functional brain activity,
oxygen metabolism, and neurovascular factors. Accurate interpretation of the BOLD signal …

nNOS-expressing interneurons control basal and behaviorally evoked arterial dilation in somatosensory cortex of mice

CT Echagarruga, KW Gheres, JN Norwood, PJ Drew - Elife, 2020 - elifesciences.org
Cortical neural activity is coupled to local arterial diameter and blood flow. However, which
neurons control the dynamics of cerebral arteries is not well understood. We dissected the …

[HTML][HTML] Neurobiological divergence of the positive and negative schizophrenia subtypes identified on a new factor structure of psychopathology using non-negative …

J Chen, KR Patil, S Weis, K Sim, T Nickl-Jockschat… - Biological …, 2020 - Elsevier
Background Disentangling psychopathological heterogeneity in schizophrenia is
challenging, and previous results remain inconclusive. We employed advanced machine …

Rude mechanicals in brain haemodynamics: non-neural actors that influence blood flow

A Das, K Murphy, PJ Drew - … Transactions of the Royal …, 2021 - royalsocietypublishing.org
Fluctuations in blood oxygenation and flow are widely used to infer brain activity during
resting-state functional magnetic resonance imaging (fMRI). However, there are strong …

The effects of age on resting‐state BOLD signal variability is explained by cardiovascular and cerebrovascular factors

KA Tsvetanov, RNA Henson, PS Jones… - …, 2021 - Wiley Online Library
Accurate identification of brain function is necessary to understand neurocognitive aging,
and thereby promote health and well‐being. Many studies of neurocognitive aging have …

CO2 signaling mediates neurovascular coupling in the cerebral cortex

PS Hosford, JA Wells, S Nizari, IN Christie… - Nature …, 2022 - nature.com
Neurovascular coupling is a fundamental brain mechanism that regulates local cerebral
blood flow (CBF) in response to changes in neuronal activity. Functional imaging techniques …

Cerebral blood flow in bipolar disorder: a systematic review

S Toma, BJ MacIntosh, W Swardfager… - Journal of affective …, 2018 - Elsevier
Background Neuroimaging of cerebral blood flow (CBF) can inform our understanding of the
pathophysiology of bipolar disorder (BD) as there is increasing support for the concept that …