Hypertension is the most common chronic disease in the world, yet the precise cause of
elevated blood pressure often cannot be determined. Animal models have been useful for …

Men have higher blood pressure than women through much of life regardless of race and
ethnicity. This is a robust and highly conserved sex difference that it is also observed across …

Gut dysbiosis has been linked to cardiovascular diseases including hypertension. We tested
the hypothesis that hypertension could be induced in a normotensive strain of rats or …

Hypertension and atherosclerosis are among the most common causes of mortality in both
developed and developing countries. Experimental animal models of hypertension and …

Hypertension or high blood pressure is a significant health problem worldwide. Bioactive
peptides that inhibit angiotensin I converting enzyme (ACE) in the cardiovascular system …

Nearly one-third of deaths in the United States are caused by cardiovascular disease (CVD)
each year. In the past, CVD was thought to mainly affect men, leading to the exclusion of …

Hypertension is a multifaceted disease that is involved in∼ 40% of cardiovascular
mortalities and is the result of both genetic and environmental factors. Because of its …

The existence of a mammalian family of TRPC ion channels, direct homologues of TRP, the
visual transduction channel of flies, was discovered during 1995–1996 as a consequence of …

Mice lacking natriuretic peptide receptor A (NPRA) have marked cardiac hypertrophy and
chamber dilatation disproportionate to their increased blood pressure (BP), suggesting, in …

Hypertension is a multifactorial disease involving complex interactions between genetic and
environmental factors. Development of experimental models of hypertension allowed …