Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …

The use of fluorescent nucleic acid base analogues is becoming increasingly important in
the fields of biology, biochemistry and biophysical chemistry as well as in the field of DNA …

Fluorescence labeling and probing are fundamental techniques for nucleic acid analysis
and quantification. However, new fluorescent probes and approaches are urgently needed …

A fluorescent ribonucleoside alphabet consisting of highly emissive purine (th A, th G) and
pyrimidine (th U, th C) analogues, all derived from thieno [3, 4-d] pyrimidine as the …

Base‐modified fluorescent nucleoside analog probes have been very valuable in the study
of nucleic acid structure and function. Many of them structurally resemble natural bases, and …

Modified nucleosides possessing intrinsically fluorescent heterocycles as base surrogates
that are capable of canonical basepairing are becoming important biomolecular tools. These …

Pd/Cu-mediated direct arylation of 2′-deoxyadenosine with various aryl iodides provides 8-
arylated 2′-deoxyadenosine derivatives in good yields. Following significant reaction …

The design of four new fluorinated biaryl fluorescent labels and their attachment to
nucleosides and nucleoside triphosphates (dNTPs) by the aqueous cross-coupling …

Guanosines with substituents at the 8-position can provide useful fluorescent probes that
effectively mimic guanine residues even in highly demanding model systems such as …

A robust analysis and discovery platform for antibiotics targeting the bacterial rRNA A-site
has been developed by incorporating a new emissive U surrogate into the RNA and labeling …