Since the emergence of SARS-CoV-2, many genetic variations within its genome have been
identified, but only a few mutations have been found in nonstructural proteins (NSPs) …

Abstract Phosphodiesterase type 5 (PDE5) is a multidomain protein that plays a crucial role
in regulating cellular cyclic guanosine monophosphate (cGMP), a key signaling molecule …

Nucleotide-binding site (NBS) domain genes are one of the superfamily of resistance genes
involved in plant responses to pathogens. The current study identified 12,820 NBS-domain …

The African Swine Fever virus (ASFV) causes an infectious viral disease in pigs of all ages.
The development of antiviral drugs primarily aimed at inhibition of proteases required for the …

Transforming growth factor β1 (TGF‐β) is a cytokine with pleiotropic biological functions.
Recently, its signaling pathway has been highlighted for its implicative paradoxical roles in …

The functional similarity among terms of an ontology is evaluated by using Semantic
Similarity Measures (SSM). In computational biology, biological entities such as genes or …

Vaccination approaches that may provide protection against the abnormal form of prion
protein (PrPSc) have recently focused on the ability of antibodies to prevent PrPSc …

AI-based approaches have been recently applied to in silico drug design. However, existing
approaches and protocols consider the absorption, distribution, metabolism, excretion, and …

The number of cloud users is rapidly growing in a cloud computing environment, which
increases the need for resources. Virtual machine migration, which involves moving the …

Large genomic projects such as The Cancer Genome Atlas (TCGA) offer a great opportunity
to conquer the challenge of distinguishing the driver somatic mutations from passenger …