Epidemiology and management of aortic disease: aortic aneurysms and acute aortic syndromes

E Bossone, KA Eagle - Nature Reviews Cardiology, 2021 - nature.com
The aorta is the 'greatest artery', through which oxygenated blood is delivered from the left
ventricle to end organs with each cardiac cycle (200 million litres of blood transported in an …

[HTML][HTML] Techniques for characterizing mechanical properties of soft tissues

K Navindaran, JS Kang, K Moon - Journal of the Mechanical Behavior of …, 2023 - Elsevier
The characterization of soft tissues remains a vital need for various bioengineering and
medical fields. Developing areas such as regenerative medicine, robot-aided surgery, and …

Nicotine and vascular dysfunction

AK Whitehead, AP Erwin, X Yue - Acta Physiologica, 2021 - Wiley Online Library
Cigarette smoking is the single most important risk factor for the development of
cardiovascular diseases (CVDs). However, the role of nicotine, the addictive component of …

E-cigarettes and cardiopulmonary health

R Tarran, RG Barr, NL Benowitz, A Bhatnagar… - Function, 2021 - academic.oup.com
E-cigarettes have surged in popularity over the last few years, particularly among youth and
young adults. These battery-powered devices aerosolize e-liquids, comprised of propylene …

Long-term electronic cigarette exposure induces cardiovascular dysfunction similar to tobacco cigarettes: role of nicotine and exposure duration

MA El-Mahdy, EM Mahgoup… - American Journal …, 2021 - journals.physiology.org
Electronic cigarette (e-cig) vaping (ECV) has been proposed as a safer alternative to
tobacco cigarette smoking (TCS); however, this remains controversial due to a lack of long …

Pathogenic mechanisms and the potential of drug therapies for aortic aneurysm

B Liu, DJ Granville, J Golledge… - American Journal of …, 2020 - journals.physiology.org
Aortic aneurysm is a permanent focal dilation of the aorta. It is usually an asymptomatic
disease but can lead to sudden death due to aortic rupture. Aortic aneurysm-related …

[HTML][HTML] Translating mouse models of abdominal aortic aneurysm to the translational needs of vascular surgery

A Busch, S Bleichert, N Ibrahim, M Wortmann… - JVS-vascular …, 2021 - Elsevier
Introduction Abdominal aortic aneurysm (AAA) is a condition that has considerable
socioeconomic impact and an eventual rupture is associated with high mortality and …

Electronic cigarette exposure disrupts blood-brain barrier integrity and promotes neuroinflammation

NA Heldt, A Seliga, M Winfield, S Gajghate… - Brain, behavior, and …, 2020 - Elsevier
Electronic cigarette (e-cigarette) use has grown substantially since inception, particularly
among adolescents and combustible tobacco users. Several cigarette smoke constituents …

A 6-month systems toxicology inhalation study in ApoE−/− mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke

J Szostak, ET Wong, B Titz, T Lee… - American Journal …, 2020 - journals.physiology.org
Smoking cigarettes is harmful to the cardiovascular system. Considerable attention has
been paid to the reduced harm potential of alternative nicotine-containing inhalable …

Dynamic crosstalk between vascular smooth muscle cells and the aged extracellular matrix

JC Ribeiro-Silva, P Nolasco, JE Krieger… - International journal of …, 2021 - mdpi.com
Vascular aging is accompanied by the fragmentation of elastic fibers and collagen
deposition, leading to reduced distensibility and increased vascular stiffness. A rigid artery …