Hydrogels for protein delivery

T Vermonden, R Censi, WE Hennink - Chemical reviews, 2012 - ACS Publications
Importantly, with the advent of hybridoma and recombinant DNA technologies, the limitations
associated with the extraction and purification of pharmaceutical proteins from animal …

Hydrogels for tissue engineering

KY Lee, DJ Mooney - Chemical reviews, 2001 - ACS Publications
Every year, millions of patients suffer the loss or failure of an organ or tissue as a result of
accidents or disease. Over 8 million surgical procedures are performed to treat these …

25th anniversary article: designer hydrogels for cell cultures: a materials selection guide

J Thiele, Y Ma, SMC Bruekers, S Ma… - Advanced …, 2014 - Wiley Online Library
Cell culturing, whether for tissue engineering or cell biology studies, always involves placing
cells in a non‐natural environment and no material currently exist that can mimic the entire …

In situ-forming hydrogels—review of temperature-sensitive systems

E Ruel-Gariepy, JC Leroux - European Journal of Pharmaceutics and …, 2004 - Elsevier
In the past few years, an increasing number of in situ-forming systems have been reported in
the literature for various biomedical applications, including drug delivery, cell encapsulation …

Self-cross-linking biopolymers as injectable in situ forming biodegradable scaffolds

B Balakrishnan, A Jayakrishnan - Biomaterials, 2005 - Elsevier
The injectable polymer scaffolds which are biocompatible and biodegradable are important
biomaterials for tissue engineering and drug delivery. Hydrogels derived from natural …

Hydrogels and drug delivery

NA Peppas - Current opinion in colloid & interface science, 1997 - Elsevier
Recent developments include the use of water-swollen, crosslinked biomedical polymers as
carriers for the delivery of drugs, peptides and proteins, as targeting agents for site-specific …

Thermosensitive polymeric hydrogels as drug delivery systems

C Gong, T Qi, X Wei, Y Qu, Q Wu… - Current medicinal …, 2013 - ingentaconnect.com
Thermosensitive hydrogels are very important biomaterials used in drug delivery systems
(DDSs), which gained increasing attention of researchers. Thermosensitive hydrogels have …

Injectable gels for tissue engineering

A Gutowska, B Jeong… - The Anatomical Record …, 2001 - Wiley Online Library
Recently, tissue engineering approaches using injectable, in situ gel forming systems have
been reported. In this review, the gelation processes and several injectable systems that …

Synthesis and Characterization of Injectable Poly(N-isopropylacrylamide)-Based Hydrogels That Support Tissue Formation in Vitro

RA Stile, WR Burghardt, KE Healy - Macromolecules, 1999 - ACS Publications
Hydrogels that support tissue formation in vitro were developed using poly (N-
isopropylacrylamide)[P (NIPAAm)]. Loosely cross-linked P (NIPAAm) and poly (NIPAAm-co …

Injectable scaffolds for tissue regeneration

Q Hou, A Paul, KM Shakesheff - Journal of Materials Chemistry, 2004 - pubs.rsc.org
Tissue engineering aims to develop functional substitutes for damaged or diseased tissues
through complex constructs of living cells, bioactive molecules and three-dimensional …