Animal models of osteoarthritis (OA) are essential tools for investigating the development of
the disease on a more rapid timeline than human OA. Mice are particularly useful due to the …

Background: Microfracture, the standard of care, is recognized to be an incomplete solution
for cartilage damage. BST-CarGel, a chitosan-based medical device, is mixed with …

Chondrocytes are the cells within cartilage which produce and maintain the extracellular
matrix. Volume regulation in these cells is vital to their function and occurs in several …

Non-invasive techniques for quantifying early biochemical and biomechanical changes in
articular cartilage may provide a means of more precisely assessing osteoarthritis (OA) …

We compared the acute response and recovery of ultrasonography (US) cartilage outcomes
(ie, thickness, cross-sectional area, and echo intensity) between walking, drop-landing and …

Objective To determine whether the presence of definite osteophytes (in the absence of joint
space narrowing [JSN]) on radiographs is associated with (subregional) increases in …

Objective To measure the variability of T 1ρ relaxation times using CubeQuant, T 2
relaxation times using quantitative double echo in steady state (DESS), and normalized …

Chondroitin sulfate (CS) is the most abundant glycosaminoglycan (GAG) in articular
cartilage and the loss of CS-GAG occurs early in OA. As a major component of perichondral …

Small animal models are essential for studying anterior cruciate ligament (ACL) injury, one
of the leading risk factors for post‐traumatic osteoarthritis (PTOA). Non‐surgical models of …

The present study aimed to investigate the biological function and underlying molecular
mechanisms of miR-31 in osteoarthritis (OA). Reverse transcription‑quantitative polymerase …