H Liu, J Weng, CLH Huang, AP Jackson - Biomarker Research, 2024 - Springer
Voltage-gated sodium channels (VGSCs) initiate action potentials in electrically excitable cells and tissues. Surprisingly, some VGSC genes are aberrantly expressed in a variety of …
SN Mbugua - Bioinorganic Chemistry and Applications, 2022 - Wiley Online Library
Solid tumors have a unique tumor microenvironment (TME), which includes hypoxia, low acidity, and high hydrogen peroxide and glutathione (GSH) levels, among others. These …
X Hou, J Ouyang, L Tang, P Wu, X Deng, Q Yan… - Plos …, 2024 - journals.plos.org
Breast cancer is the most prevalent malignancy and the most significant contributor to mortality in female oncology patients. Potassium Two Pore Domain Channel Subfamily K …
R Moreddu - Advanced Science, 2024 - Wiley Online Library
Bioelectricity is the electrical activity that occurs within living cells and tissues. This activity is critical for regulating homeostatic cellular function and communication, and disruptions of …
MBA Djamgoz - Cancer and Metastasis Reviews, 2024 - Springer
The normal functioning of every cell in the body depends on its bioelectric properties and many diseases are caused by genetic and/or epigenetic dysregulation of the underlying ion …
M Li, P Tian, Q Zhao, X Ma, Y Zhang - Frontiers in Oncology, 2023 - frontiersin.org
In recent years, the role of potassium channels in tumors has been intensively studied. Potassium channel proteins are widely involved in various physiological and pathological …
C Xia, C Liu, S Ren, Y Cai, Q Zhang, C Xia - Biomedicine & …, 2023 - Elsevier
Potassium channels play an important role in human physiological function. Recently, various molecular mechanisms have implicated abnormal functioning of potassium …
In recent decades, medical research has been primarily focused on the inherited aspect of cancers, despite the reality that only 5–10% of tumours discovered are derived from genetic …