Western lifestyle contributes to an overt increase in the prevalence of metabolic anomalies
including diabetes mellitus (DM) and obesity. Prevalence of DM is rapidly growing …

Bergenin is a glycosidic derivative of trihydroxybenzoic acid that was discovered in 1880 by
Garreau and Machelart from the rhizomes of the medicinal plant Bergenia crassifolia …

Oxidative stress, resulting from an imbalance between the formation of damaging free
radicals and availability of protective antioxidants, can contribute to peripheral neuropathic …

Diabetes has become more common in recent years worldwide, and this growth is projected
to continue in the future. The primary concern with diabetes is developing various …

Liver fibrosis is a pathological process involving diffuse extracellular matrix (ECM)
deposition in the liver. It is typical of many chronic liver diseases, including cirrhosis, and …

Diabetes is linked with various microvascular and macrovascular complications.
Nephropathy, neuropathy and retinopathy are important microvascular complications of …

Background: Bergenin, 4-O-methyl gallic acid glucoside, is a bioactive compound found in
the cortex of Mallotus japonicus (Lf) Müll. Arg. along with many other natural resources …

Background Diabetic neuropathy (DN) is a serious microvascular complication and a major
cause of morbidity and mortality in diabetes mellitus. It is characterized by …

Chemotherapy-induced neuropathic pain (CINP) is one of the most prominent and
incapacitating complication associated with chemotherapeutic regimens. The exact …

The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) has multifarious
action with its target genes having redox‐regulating functions and being involved in …