Single-cell proteomics: progress and prospects

RT Kelly - Molecular & Cellular Proteomics, 2020 - ASBMB
MS-based proteome profiling has become increasingly comprehensive and quantitative, yet
a persistent shortcoming has been the relatively large samples required to achieve an in …

[HTML][HTML] Additive manufacturing (3D printing) for analytical chemistry

H Agrawaal, JE Thompson - Talanta Open, 2021 - Elsevier
In recent years, 3D printing, also known as additive manufacturing, has received
unprecedented level of interest and attention in the field of analytical chemistry due to its …

Micro gas chromatography: An overview of critical components and their integration

BP Regmi, M Agah - Analytical chemistry, 2018 - ACS Publications
Among a number of gas analyzers, portable gas chromatography (GC) systems created by
the integration of microfabricated components are promising candidates for rapid and on …

Advances and innovations in liquid chromatography stationary phase supports

K Broeckhoven, G Desmet - Analytical Chemistry, 2020 - ACS Publications
The continuous evolution of stationary phase supports over the past decades have allowed
a vast increase the separation performance in liquid chromatography. As in any …

Transport in nanofluidic systems: a review of theory and applications

W Sparreboom, A van den Berg… - New Journal of …, 2010 - iopscience.iop.org
In this paper transport through nanochannels is assessed, both of liquids and of dissolved
molecules or ions. First, we review principles of transport at the nanoscale, which will involve …

On-chip comparison of the performance of first-and second-generation micropillar array columns

B Vankeerberghen, J Op de Beeck… - Analytical …, 2023 - ACS Publications
Because of its dimensions, the recently introduced micropillar array columns are most suited
for high-efficiency liquid chromatography separations in proteomics. Unlike the packed bed …

The rise of single‐cell proteomics

C Ctortecka, K Mechtler - Analytical Science Advances, 2021 - Wiley Online Library
Mass spectrometry‐based proteomics comprehensively defines proteome expression
patterns in thousands of cells majorly contributing to our current understanding of many …

Fundamentals for LC miniaturization

G Desmet, S Eeltink - Analytical chemistry, 2013 - ACS Publications
Whereas a huge surge in the development of miniaturized LC systems was marking the field
in the 1970s and 1980s of the past century, 1− 3 the academic interest in the topic declined …

Fundamental and practical insights on the packing of modern high-efficiency analytical and capillary columns

MF Wahab, DC Patel, RM Wimalasinghe… - Analytical …, 2017 - ACS Publications
New stationary phases are continuously developed for achieving higher efficiencies and
unique selectivities. The performance of any new phase can only be assessed when the …

Miniaturization of liquid chromatography coupled to mass spectrometry: 1. Current trends on miniaturized LC columns

K Mejia-Carmona, JS da Silva Burato… - TrAC Trends in …, 2020 - Elsevier
Over the last decade, the use of miniaturized columns in liquid chromatography (LC) has
seen intense growth in a wide range of research areas. This report brings an overview of the …