Hereditary transthyretin amyloidosis (ATTRv) is a severe, adult-onset autosomal dominant
inherited systemic disease predominantly affecting the peripheral and autonomic nervous …

ATTR amyloidosis is caused by systemic deposition of transthyretin (TTR) and comprises
ATTRwt (wt for wild-type) amyloidosis, ATTRv (v for variant) amyloidosis, and acquired ATTR …

Transthyretin familial amyloid polyneuropathy (TTR-FAP) is a progressive, fatal, inherited
disorder first identified in Portugal and now recognized in all continents. Over the past …

Hereditary transthyretin amyloidosis (ATTRv) is a condition with adult onset, caused by
mutation of the transthyretin (TTR) gene and characterized by extracellular deposition of …

Hereditary transthyretin (TTR) amyloid polyneuropathy is an autosomal dominant life-
threatening disorder. TTR is produced mainly by the liver but also by the choroid plexus and …

Amyloidosis caused by systemic deposition of transthyretin (TTR) is called ATTR
amyloidosis and mainly includes hereditary ATTR (ATTRv) amyloidosis and wild-type ATTR …

Peripheral neuropathy occurs in the setting of both hereditary and acquired amyloidosis.
The most common form of hereditary amyloidosis is caused by 1 of 140 mutations in the …

Background Diagnostic delay of hereditary transthyretin amyloidosis (ATTRv, v for variant)
prevents timely treatment and, therefore, concurs to the mortality of the disease. The aim of …

Transthyretin (TTR) amyloidosis is caused by systemic deposition of wild-type or variant
amyloidogenic TTR (ATTRwt and ATTRv, respectively). ATTRwt amyloidosis has …

Hereditary transthyretin amyloidosis (ATTRm) causes a disabling peripheral neuropathy as
part of a multisystem disorder. The recent development of highly effective gene silencing …