Recent developments in the synthesis of N‐heterocyclic compounds as α‐amylase inhibitors via in‐vitro and in‐silico analysis: Future drugs for treating diabetes

P Garg, RS Rawat, H Bhatt, S Kumar… - …, 2022 - Wiley Online Library
In nature, N‐heterocyclic compounds and their derivatives are abundant. They serve as the
building blocks of many biological entities, such as enzymes, alkaloids, hormones …

Development in the Synthesis of Bioactive Thiazole-Based Heterocyclic Hybrids Utilizing Phenacyl Bromide

G Kumari, S Dhillon, P Rani, M Chahal, DK Aneja… - ACS …, 2024 - ACS Publications
Heterocyclic hybrid frameworks represent a burgeoning domain within the realms of drug
discovery and medicinal chemistry, attracting considerable attention in recent years …

Synthesis, Type II diabetes inhibitory activity, antimicrobial evaluation and docking studies of indeno[1,2-c]pyrazol-4(1H)-ones

S Mor, S Sindhu - Medicinal Chemistry Research, 2020 - Springer
We report a convenient and efficient synthesis of indeno [1, 2-c] pyrazol-4 (1 H)-ones (4a‒o)
by the reaction of a variety of 2-acyl-(1 H)-indene-1, 3 (2 H)-diones (1) and 2 …

Synthesis, biological evaluation, migratory inhibition and docking study of indenopyrazolones as potential anticancer agents

N Hosseini Nasab, Y Han, F Hassan Shah… - Chemistry & …, 2022 - Wiley Online Library
Some bioactive derivatives of indeno [1, 2‐c] pyrazolones were synthesized through the
reaction of phenylhydrazine, different aldehydes and indan‐1, 2, 3‐trione at room …

Nano-Fe3O4–Cysteine as a Superior Catalyst for the Synthesis of Indeno[1,2-c]pyrazol-4(1H)-ones

J Safaei-Ghomi, SM Ebrahimi - Polycyclic Aromatic Compounds, 2022 - Taylor & Francis
Abstract Nano-Fe3O4–l-cysteine as a superior catalyst has been used for the synthesis of
indeno [1, 2-c] pyrazol-4 (1H)-ones through a three-component reaction of phenylhydrazine …

[HTML][HTML] Antimicrobial evaluation and QSAR studies of 3, 6-disubstituted-11H-benzo [5, 6][1, 4] thiazino [3, 4-a] isoindol-11-ones

S Mor, S Sindhu, M Khatri, R Punia, H Sandhu… - European Journal of …, 2022 - Elsevier
The antimicrobial evaluation of a series of twenty 3, 6-disubstituted-11H-benzo [5, 6][1, 4]
thiazino [3, 4-a] isoindol-11-ones 8a–t was done against two Gram-positive bacterial strains …

Zn (II) complex with pyridine based 1, 3-selenazolyl-hydrazone: Synthesis, structural characterization and DFT study

J Araškov, P Ristić, A Višnjevac, D Mitić… - Journal of the …, 2023 - cherry.chem.bg.ac.rs
An octahedral complex of Zn (II) with a ligand from a class of pyridine-based 1, 3-selenazolyl-
hydrazones was synthesized and characterized by IR and NMR spectroscopy and single …

[PDF][PDF] Synthesis, Type II diabetes inhibitory activity, antimicrobial evaluation, and docking studies of N'-arylidene-2-((7-methylbenzo [4, 5] thiazolo [2, 3-c][1, 2, 4] triazol …

S Mor, S Sindhu, M Khatri, R Punia… - European Journal of …, 2022 - academia.edu
Diabetes mellitus is a metabolic disorder resulting from insufficient insulin secretion
characterized by chronic hyperglycemia due to high-calorie diets rich in carbohydrates, fats …

HPA-ZSM-5 nanocomposite as high-performance catalyst for the synthesis of indenopyrazolones

SM Ebrahimi, J Safaei-Ghomi… - Main Group Metal …, 2022 - degruyter.com
Abstract tHPA-ZSM-5 nanocomposites as a superior catalyst have been applied for the
synthesis of indenopyrazolones through a three-component reaction of phenylhydrazine …

[HTML][HTML] Synthesis of indenopyrazolones using functionalized SBA-15

H Shahbazi-Alavi, A Bakhtiari… - Nanochemistry …, 2021 - nanochemres.org
Functionalized SBA-15 (Immobilization of Pd on the modified SBA-15) has been applied as
an efficient catalyst for the preparation of indenopyrazolones by multi-component reactions …