The Interface of Vibrio cholerae and the Gut Microbiome
The bacterium Vibrio cholerae is the etiologic agent of the severe human diarrheal disease
cholera. The gut microbiome, or the native community of microorganisms found in the …
cholera. The gut microbiome, or the native community of microorganisms found in the …
Protection afforded by previous Vibrio cholerae infection against subsequent disease and infection: A review
Background Cholera is an acute, diarrheal disease caused by Vibrio cholerae O1 or 139
that is associated with a high global burden. Methods We analyzed the estimated duration of …
that is associated with a high global burden. Methods We analyzed the estimated duration of …
Evolutionary sweeps of subviral parasites and their phage host bring unique parasite variants and disappearance of a phage CRISPR-Cas system
Vibrio cholerae is a significant threat to global public health in part due to its propensity for
large-scale evolutionary sweeps where lineages emerge and are replaced. These sweeps …
large-scale evolutionary sweeps where lineages emerge and are replaced. These sweeps …
Identification and genomic analysis of a Vibrio cholerae strain isolated from a patient with bloodstream infection
Y Ding, J Hao, Z Zeng, J Liu - Heliyon, 2022 - cell.com
Vibrio cholerae is a bacterium ubiquitous in aquatic environments which can cause
widespread infection worldwide. V. cholerae gradually became a rare species of bacteria in …
widespread infection worldwide. V. cholerae gradually became a rare species of bacteria in …
Long-Term Kinetics of Serological Antibodies against Vibrio cholerae Following a Clinical Cholera Case: A Systematic Review and Meta-Analysis
Background: Approximately 2.9 million people worldwide suffer from cholera each year,
many of whom are destitute. However, understanding of immunity against cholera is still …
many of whom are destitute. However, understanding of immunity against cholera is still …
Systemic, mucosal, and memory immune responses following cholera
Vibrio cholerae O1, the major causative agent of cholera, remains a significant public health
threat. Although there are available vaccines for cholera, the protection provided by killed …
threat. Although there are available vaccines for cholera, the protection provided by killed …
Cholera toxin and O-specific polysaccharide immune responses after oral cholera vaccination with Dukoral in different age groups of Bangladeshi participants
Vaccination is important to prevent cholera. There are limited data comparing anti-O-specific
polysaccharide (OSP) and anti-cholera toxin-specific immune responses following oral …
polysaccharide (OSP) and anti-cholera toxin-specific immune responses following oral …
[HTML][HTML] Parenteral vaccination with a cholera conjugate vaccine boosts vibriocidal and anti-OSP responses in mice previously immunized with an oral cholera …
A Akter, M Kelly, RC Charles, JB Harris… - The American Journal …, 2021 - ncbi.nlm.nih.gov
Oral cholera vaccination protects against cholera; however, responses in young children are
low and of short duration. The best current correlates of protection against cholera target …
low and of short duration. The best current correlates of protection against cholera target …
Defining polysaccharide-specific antibody targets against Vibrio cholerae O139 in humans following O139 cholera and following vaccination with a commercial …
M Kamruzzaman, M Kelly, RC Charles, JB Harris… - Msphere, 2021 - Am Soc Microbiol
Cholera caused by Vibrio cholerae O139 could reemerge, and proactive development of an
effective O139 vaccine would be prudent. To define immunoreactive and potentially …
effective O139 vaccine would be prudent. To define immunoreactive and potentially …
A dysbiotic gut microbiome suppresses antibody mediated-protection against Vibrio cholerae
Cholera is a severe diarrheal disease that places a significant burden on global health.
Cholera's high morbidity demands effective prophylactic strategies, but oral cholera …
Cholera's high morbidity demands effective prophylactic strategies, but oral cholera …