Layer 1 neocortex: Gating and integrating multidimensional signals

S Huang, SJ Wu, G Sansone, LA Ibrahim, G Fishell - Neuron, 2024 - cell.com
Summary Layer 1 (L1) of the neocortex acts as a nexus for the collection and processing of
widespread information. By integrating ascending inputs with extensive top-down activity …

[HTML][HTML] Cooperative thalamocortical circuit mechanism for sensory prediction errors

S Furutachi, AD Franklin, AM Aldea, TD Mrsic-Flogel… - Nature, 2024 - nature.com
The brain functions as a prediction machine, utilizing an internal model of the world to
anticipate sensations and the outcomes of our actions. Discrepancies between expected …

How 'visual'is the visual cortex? The interactions between the visual cortex and other sensory, motivational and motor systems as enabling factors for visual perception

CMA Pennartz, MN Oude Lohuis… - … Transactions of the …, 2023 - royalsocietypublishing.org
The definition of the visual cortex is primarily based on the evidence that lesions of this area
impair visual perception. However, this does not exclude that the visual cortex may process …

Cell-type-specific plasticity of inhibitory interneurons in the rehabilitation of auditory cortex after peripheral damage

M Kumar, G Handy, S Kouvaros, Y Zhao… - Nature …, 2023 - nature.com
Peripheral sensory organ damage leads to compensatory cortical plasticity that is
associated with a remarkable recovery of cortical responses to sound. The precise …

Transcriptomic cell-type specificity of local cortical circuits

M Patiño, MA Rossa, WN Lagos, NS Patne… - Neuron, 2024 - cell.com
Complex neocortical functions rely on networks of diverse excitatory and inhibitory neurons.
While local connectivity rules between major neuronal subclasses have been established …

A frontal transcallosal inhibition loop mediates interhemispheric balance in visuospatial processing

Y Wang, Z Chen, G Ma, L Wang, Y Liu, M Qin… - Nature …, 2023 - nature.com
Interhemispheric communication through the corpus callosum is required for both sensory
and cognitive processes. Impaired transcallosal inhibition causing interhemispheric …

Flexible neural population dynamics govern the speed and stability of sensory encoding in mouse visual cortex

EAB Horrocks, FR Rodrigues, AB Saleem - Nature Communications, 2024 - nature.com
Time courses of neural responses underlie real-time sensory processing and perception.
How these temporal dynamics change may be fundamental to how sensory systems adapt …

Regional and cell-type-specific afferent and efferent projections of the mouse claustrum

Q Wang, Y Wang, HC Kuo, P Xie, X Kuang… - Cell reports, 2023 - cell.com
The claustrum (CLA) is a conspicuous subcortical structure interconnected with cortical and
subcortical regions. Its regional anatomy and cell-type-specific connections in the mouse …

Population encoding of stimulus features along the visual hierarchy

L Dyballa, AM Rudzite, MS Hoseini… - Proceedings of the …, 2024 - National Acad Sciences
The retina and primary visual cortex (V1) both exhibit diverse neural populations sensitive to
diverse visual features. Yet it remains unclear how neural populations in each area partition …

General anesthesia activates a central anxiolytic center in the BNST

D Lu, CGU Lavergne, S Choi, J Park, J Kim, S Zhao… - Cell reports, 2024 - cell.com
Low doses of general anesthetics like ketamine and dexmedetomidine have anxiolytic
properties independent of their sedative effects, but the underlying mechanisms remain …