The blood–brain barrier (BBB) is a highly specialized neurovascular unit, initially described
as an intact barrier to prevent toxins, pathogens, and potentially harmful substances from …

Brain glucose metabolism, including glycolysis, the pentose phosphate pathway, and
glycogen turnover, produces ATP for energetic support and provides the precursors for the …

Stroke is the leading cause of disability among adults as well as the 2nd leading cause of
death globally. Ischemic stroke accounts for about 85% of strokes, and currently, tissue …

In recent times, there has been a significant increase in researchers' interest in the functions
of microRNAs and the role of these molecules in the pathogenesis of many multifactorial …

Over the past decade, there has been an uptick in the number of studies conducting
research on the role of microRNA (miRNA) molecules in stroke. Among these molecules …

Acute stroke causes complex, pathological, and systemic responses that have not been
treatable by any single medication. In this study, using a murine transient middle cerebral …

The blood-brain barrier (BBB), which controls permeability into and out of the nervous
system, is a tightly connected, structural, and functional separation between the central …

Mitochondria are double-membrane organelles that provide the majority of a cell's energy.
Furthermore, mitochondria are involved in various cellular biological activities, including …

The review introduces the stages of formation and experimental confirmation of the
hypothesis regarding the mutual potentiation of neuroprotective effects of hypoxia and …

Atherogenesis involves multiple cell types undergoing robust metabolic processes resulting
in mitochondrial dysfunction, elevated reactive oxygen species (ROS), and consequent …