Health benefits and side effects of short-chain fatty acids

RG Xiong, DD Zhou, SX Wu, SY Huang, A Saimaiti… - Foods, 2022 - mdpi.com
The gut microbiota and their metabolites could play an important role in health and diseases
of human beings. Short-chain fatty acids (SCFAs) are mainly produced by gut microbiome …

Short chain fatty acids: microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

[HTML][HTML] Health benefits of resistant starch: A review of the literature

A Bojarczuk, S Skąpska, AM Khaneghah… - Journal of functional …, 2022 - Elsevier
Starch is an essential source of energy for the human diet. Resistant starch is the portion of
starch that is not digested in the small intestine and is fermented in the colon by …

[HTML][HTML] Role of microbiota-derived short-chain fatty acids in cancer development and prevention

R Mirzaei, A Afaghi, S Babakhani, MR Sohrabi… - Biomedicine & …, 2021 - Elsevier
Following cancer, cells in a particular tissue can no longer respond to the factors involved in
controlling cell survival, differentiation, proliferation, and death. In recent years, it has been …

Microbiota-derived metabolites as drivers of gut–brain communication

H Ahmed, Q Leyrolle, V Koistinen, O Kärkkäinen… - Gut …, 2022 - Taylor & Francis
Alterations in the gut microbiota composition have been associated with a range of
neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. The gut microbes …

The role of short-chain fatty acids in microbiota–gut–brain communication

B Dalile, L Van Oudenhove, B Vervliet… - Nature reviews …, 2019 - nature.com
Short-chain fatty acids (SCFAs), the main metabolites produced by bacterial fermentation of
dietary fibre in the gastrointestinal tract, are speculated to have a key role in microbiota–gut …

[HTML][HTML] Gut microbiota-derived short chain fatty acids are potential mediators in gut inflammation

M Akhtar, Y Chen, Z Ma, X Zhang, D Shi, JA Khan… - Animal nutrition, 2022 - Elsevier
Gut inflammation is a challenging concern in humans and animals, which disturbs normal
growth and leads to severe bowel diseases. Short chain fatty acids (SCFA) are the gut …

Brain–gut–microbiome interactions in obesity and food addiction

A Gupta, V Osadchiy, EA Mayer - Nature Reviews Gastroenterology & …, 2020 - nature.com
Normal eating behaviour is coordinated by the tightly regulated balance between intestinal
and extra-intestinal homeostatic and hedonic mechanisms. By contrast, food addiction is a …

Short-chain fatty acids as potential regulators of skeletal muscle metabolism and function

J Frampton, KG Murphy, G Frost, ES Chambers - Nature metabolism, 2020 - nature.com
A key metabolic activity of the gut microbiota is the fermentation of non-digestible
carbohydrate, which generates short-chain fatty acids (SCFAs) as the principal end …

Modified prebiotic-based “shield” armed probiotics with enhanced resistance of gastrointestinal stresses and prolonged intestinal retention for synergistic alleviation of …

A Xie, H Ji, Z Liu, Y Wan, X Zhang, H Xiong, SP Nie… - ACS …, 2023 - ACS Publications
Oral administration of probiotics is a promising method to alleviate inflammatory bowel
diseases (IBDs). However, gastrointestinal environmental sensitivity and inferior intestinal …