Enteroviral replication reorganizes the cellular membrane. Upon infection, viral proteins and
hijacked host factors generate unique structures called replication organelles (ROs) to …

The introduction of Asn‐linked glycans to nascent polypeptides occurs in the lumen of the
endoplasmic reticulum of eukaryotic cells. After the removal of specific sugar residues …

Glycoproteins traversing the eukaryotic secretory pathway begin life in the endoplasmic
reticulum (ER), where their folding is surveyed by the 170-kDa UDP-glucose: glycoprotein …

In the past decades, many studies reported the presence of endoplasmic reticulum (ER)‐
resident proteins in the cytosol. However, the mechanisms by which these proteins relocate …

Infection by enteroviruses can cause severe neurological complications in humans. The
interactions between the enteroviral and host proteins may facilitate the virus replication and …

The Picornaviridae are a large group of positive-sense, single-stranded RNA viruses, and
most research has focused on the Enterovirus genus, given they present a severe health risk …

3D polymerase, also known as RNA-dependent RNA polymerase, is encoded by all known
picornaviruses, and their structures are highly conserved. In the process of picornavirus …

Enteroviruses, which may cause neurological complications, have become a public health
threat worldwide in recent years. Interactions between cellular proteins and enteroviral …

Motivated by the critical need to identify new treatments for COVID-19, we present a genome-
scale, systems-level computational approach to prioritize drug targets based on their …

ABSTRACT Enterovirus A71 (EV-A71) can cause hand, foot and mouth disease with
neurological and systemic complications, most frequently affecting children and infants. We …