[HTML][HTML] Neural tissue engineering with structured hydrogels in CNS models and therapies
The development of techniques to create and use multiphase microstructured hydrogels
(granular hydrogels or microgels) has enabled the generation of cultures with more …
(granular hydrogels or microgels) has enabled the generation of cultures with more …
[HTML][HTML] Hydrogel-assisted neuroregeneration approaches towards brain injury therapy: A state-of-the-art review
VA Kornev, EA Grebenik, AB Solovieva… - Computational and …, 2018 - Elsevier
Recent years have witnessed the development of an enormous variety of hydrogel-based
systems for neuroregeneration. Formed from hydrophilic polymers and comprised of up to …
systems for neuroregeneration. Formed from hydrophilic polymers and comprised of up to …
Construction of adhesive and bioactive silk fibroin hydrogel for treatment of spinal cord injury
Y Liu, Z Zhang, Y Zhang, B Luo, X Liu, Y Cao, R Pei - Acta Biomaterialia, 2023 - Elsevier
Spinal cord injury (SCI) often causes severe and permanent disabilities due to the
complexity of injury progression. The promising methods are generally based on tissue …
complexity of injury progression. The promising methods are generally based on tissue …
Modeling of three-dimensional innervated epidermal like-layer in a microfluidic chip-based coculture system
Reconstruction of skin equivalents with physiologically relevant cellular and matrix
architecture is indispensable for basic research and industrial applications. As skin-nerve …
architecture is indispensable for basic research and industrial applications. As skin-nerve …
Peripheral nerve injury: current challenges, conventional treatment approaches, and new trends in biomaterials-based regenerative strategies
R López-Cebral, J Silva-Correia, RL Reis… - ACS Biomaterials …, 2017 - ACS Publications
Damage to peripheral nerves is a widely extended health problem, causing important
socioeconomic costs worldwide. Indeed, peripheral nerve injuries (PNI) have been …
socioeconomic costs worldwide. Indeed, peripheral nerve injuries (PNI) have been …
Toward a neurospheroid niche model: Optimizing embedded 3D bioprinting for fabrication of neurospheroid brain-like co-culture constructs
A crucial step in creating reliable in vitro platforms for neural development and disorder
studies is the reproduction of the multicellular three-dimensional (3D) brain …
studies is the reproduction of the multicellular three-dimensional (3D) brain …
Nanotechnology in peripheral nerve repair and reconstruction
The recent progress in biomaterials science and development of tubular conduits (TCs) still
fails in solving the current challenges in the treatment of peripheral nerve injuries (PNIs), in …
fails in solving the current challenges in the treatment of peripheral nerve injuries (PNIs), in …
[HTML][HTML] 3D biomaterial models of human brain disease
Inherent limitations of the traditional approaches to study brain function and disease, such
as rodent models and 2D cell culture platforms, have led to the development of 3D in vitro …
as rodent models and 2D cell culture platforms, have led to the development of 3D in vitro …
Fundamentals and current strategies for peripheral nerve repair and regeneration
A body of evidence indicates that peripheral nerves have an extraordinary yet limited
capacity to regenerate after an injury. Peripheral nerve injuries have confounded …
capacity to regenerate after an injury. Peripheral nerve injuries have confounded …
Laminin-inspired cell-instructive microenvironments for neural stem cells
D Barros, IF Amaral, AP Pego - Biomacromolecules, 2019 - ACS Publications
Laminin is a heterotrimeric glycoprotein with a key role in the formation and maintenance of
the basement membrane architecture and properties, as well as on the modulation of …
the basement membrane architecture and properties, as well as on the modulation of …