Five individual polyphenols as tyrosinase inhibitors: Inhibitory activity, synergistic effect, action mechanism, and molecular docking

Q Yu, L Fan, Z Duan - Food chemistry, 2019 - Elsevier
Polyphenols can inhibit the enzymatic browning in food, but their indistinct synergistic effect
and conformational change have limited their applications. In this paper, the mixture of …

Natural allosteric modulators and their biological targets: molecular signatures and mechanisms

M Bruder, G Polo, DBB Trivella - Natural product reports, 2020 - pubs.rsc.org
Covering: 2008 to 2018 Over the last decade more than two hundred single natural products
were confirmed as natural allosteric modulators (alloNPs) of proteins. The compounds are …

Subcritical water extraction of red cabbage regarding cholinesterase and tyrosinase inhibitory activity

H Koyu, S Demir - Microchemical Journal, 2024 - Elsevier
Pressurized high-temperature processing of water where polarity can be regulated has been
an advanced extraction technology considering sustainable management and efficient use …

6, 7-Bis-(2-methoxyethoxy)-4 (3H)-quinazolinone as a novel inhibitor of tyrosinase and potential anti-browning agent of fresh-cut apples

WM Chai, Q Bai, Q Pan, L Wang, D Zhu - Journal of bioscience and …, 2024 - Elsevier
6, 7-Bis-(2-methoxyethoxy)-4 (3H)-quinazolinone (BMEQ) was selected from quinazolinones
for its strong tyrosinase inhibitory activity (IC 50= 160±6 μM). It suppressed tyrosinase …

Optimizing subcritical water extraction of Morus nigra L. fruits for maximization of tyrosinase inhibitory activity

H Koyu, A Kazan, TK Ozturk, O Yesil-Celiktas… - The Journal of …, 2017 - Elsevier
The process of preparing extracts for pharmaceutical industry from natural resources is a
challenge to obtain effective constituents besides using resources efficiently considering …

In silico assessment of the inhibitory effect of four flavonoids (Chrysin, Naringin, Quercetin, Kaempferol) on tyrosinase activity using the MD simulation approach

A Farasat, M Ghorbani, N Gheibi… - … Journal of Biotechnology …, 2020 - agro.icm.edu.pl
Tyrosinase is a tetrameric enzyme that plays an important role in pigment production.
Overproduction of melanin, which may lead to several skin disorders, is a result of tyrosinase …

Effect of chrysin omega‐3 and 6 fatty acid esters on mushroom tyrosinase activity, stability, and structure

Z Jamali, G Rezaei Behbehani, K Zare… - Journal of food …, 2019 - Wiley Online Library
The estreification of chrysin with α‐Linolenic acid (complex I) and linoleic acid (complex II)
poly unsaturated fatty acids resulted to design of new mushroom tyrosinase (MT) inhibitors …

Tyrosinase inhibitory effect, antioxidant and anticancer activities of bioactive compounds in ripe hog plum (Spondias pinnata) fruit extracts

S Patathananone, J Daduang… - Oriental Journal of …, 2019 - search.proquest.com
The usage of ripe hog plum fruit (Spondias pinnata) extracts in cosmetics and food products,
including cancer therapeutic agents, have a few studies. Herein, the strong anti-tyrosinase …

Biomolecular interactions and binding dynamics of inhibitor arachidonic acid, with tyrosinase enzyme

T Shojazadeh, L Zolghadr, S JafarKhani… - Journal of …, 2023 - Taylor & Francis
Hyperpigmentation is a disorder caused by increased melanin deposition and changes in
skin pigmentation. Inhibition of tyrosinase activity contributes to the control of food browning …

Kültüre alınmış Lentinula edodes' in metanol ekstraktının antioksidan ve in vitro bazı enzim inhibitör aktiviteleri

S Alkan, H Özparlak, G Zengin, G Kaşık - Mantar dergisi, 2017 - dergipark.org.tr
Shiitake mantarı adıyla da bilinen Lentinula edodes (Berk.) Pegler Doğu Asya'ya özgü
yenilebilir bir mantar olup antioksidan ve antimikrobiyal özellikleriyle tedavi edici etkiler …