Acute kidney injury (AKI) is the leading cause of nephrology consultation and is associated
with high mortality rates. The primary causes of AKI include ischemia, hypoxia or …

Rhabdomyolysis is a syndrome caused by injury to skeletal muscle that usually leads to
acute kidney injury (AKI). Rhabdomyolysis has been linked to different conditions, including …

Oxidative stress is involved in acute kidney injury due to ischemia–reperfusion and
chemotherapy-induced nephrotoxicity. To investigate their basic mechanisms we studied the …

Renal ischemia-reperfusion (IR) contributes to the development of ischemic acute renal
failure (ARF). Multi-factorial processes are involved in the development and progression of …

Drug-induced acute kidney injury (DIAKI) is associated with high morbidity and mortality. It
remains a diagnostic and therapeutic dilemma due to failure of providing unambiguous real …

Reactive oxygen species are important mediators that exert a toxic effect during ischemia-
reperfusion injury of various organs. Sulforaphane, which is a naturally occurring …

Abstract 2, 3, 5-Tris (glutathion-S-yl)-hydroquinone (TGHQ), a metabolite of hydroquinone, is
toxic to renal proximal tubule epithelial cells. TGHQ retains the ability to redox cycle and …

Mitochondrial dysfunction may play a role in the pathogenesis of several renal diseases.
Although functional roles and metabolic demands differ among tubule segments, relatively …

Background Oxidative damage is critical in the pathogenesis of ovarian
ischaemia/reperfusion (I/R) injury, and statins have been reported to exert antioxidant …

AIM: To investigate the effect of sulforaphane (SFN) on regulation of NF-E2-related factor-2
(Nrf2)-antioxidant response element (ARE) pathway in liver injury induced by intestinal …