Progress in the mechanism and targeted drug therapy for COPD

C Wang, J Zhou, J Wang, S Li, A Fukunaga… - … and Targeted Therapy, 2020 - nature.com
Chronic obstructive pulmonary disease (COPD) is emphysema and/or chronic bronchitis
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …

Postexercise hypotension and sustained postexercise vasodilatation: what happens after we exercise?

JR Halliwill, TM Buck, AN Lacewell… - Experimental …, 2013 - Wiley Online Library
New findings• What is the topic for this review? During the exercise recovery period, the
combination of centrally mediated decreases in sympathetic nerve activity with a reduced …

The thioredoxin system as a therapeutic target in human health and disease

DFD Mahmood, A Abderrazak, K El Hadri… - Antioxidants & redox …, 2013 - liebertpub.com
The thioredoxin (Trx) system comprises Trx, truncated Trx (Trx-80), Trx reductase, and
NADPH, besides a natural Trx inhibitor, the thioredoxin-interacting protein (TXNIP). This …

Mechanisms and Targeted Therapies for Pseudomonas aeruginosa Lung Infection

CS Curran, T Bolig, P Torabi-Parizi - American journal of respiratory …, 2018 - atsjournals.org
Pseudomonas aeruginosa is a complex gram-negative facultative anaerobe replete with a
variety of arsenals to activate, modify, and destroy host defense mechanisms. The microbe is …

Natural molecules targeting thioredoxin system and their therapeutic potential

J Zhang, D Duan, A Osama, J Fang - Antioxidants & Redox …, 2021 - liebertpub.com
Significance: Thioredoxin (Trx) and thioredoxin reductase are two core members of the Trx
system. The system bridges the gap between the universal reducing equivalent NADPH and …

The role of reactive oxygen species and nitric oxide in mast cell‐dependent inflammatory processes

EJ Swindle, DD Metcalfe - Immunological reviews, 2007 - Wiley Online Library
Reactive oxygen species (ROS) and reactive nitrogen oxide species (RNOS), including nitric
oxide, are produced in cells by a variety of enzymatic and non‐enzymatic mechanisms. At …

Mechanisms by which selenium influences immune responses

PR Hoffmann - Archivum immunologiae et therapiae experimentalis, 2007 - Springer
Selenium (Se) is an essential dietary trace element that influences immune responses
through its incorporation into selenoproteins as the amino acid selenocysteine. This review …

Role of reactive oxygen species in mast cell degranulation

MA Chelombitko, AV Fedorov, OP Ilyinskaya… - Biochemistry …, 2016 - Springer
Mast cells are a heterogeneous multifunctional cellular population that promotes connective
tissue homeostasis by slow release of biologically active substances, affecting primarily the …

Therapeutic potential of adipose tissue‐derivatives in modern dermatology

B Bellei, E Migliano, M Picardo - Experimental Dermatology, 2022 - Wiley Online Library
Stem cell‐mediated therapies in combination with biomaterial and growth factor‐based
approaches in regenerative medicine are rapidly evolving with increasing application …

Mesenchymal stem cells and atopic dermatitis: a review

SRT Daltro, CS Meira, IP Santos… - Frontiers in cell and …, 2020 - frontiersin.org
Mesenchymal stem/stromal cells (MSCs) are stromal-derived non-hematopoietic progenitor
cells that reside in and can be expanded from various tissues sources of adult and neonatal …