[HTML][HTML] Focus: infectious diseases: vancomycin resistance in Staphylococcus aureus

WA McGuinness, N Malachowa… - The Yale journal of …, 2017 - ncbi.nlm.nih.gov
The evolution of Staphylococcus aureus during the modern antibiotic era has been
delineated by distinct strain emergence events, many of which include acquisition of …

Antibiotic resistance in Staphylococcus aureus. Current status and future prospects

TJ Foster - FEMS microbiology reviews, 2017 - academic.oup.com
The major targets for antibiotics in staphylococci are (i) the cell envelope,(ii) the ribosome
and (iii) nucleic acids. Several novel targets emerged from recent targeted drug discovery …

Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?

A Beceiro, M Tomás, G Bou - Clinical microbiology reviews, 2013 - Am Soc Microbiol
Hosts and bacteria have coevolved over millions of years, during which pathogenic bacteria
have modified their virulence mechanisms to adapt to host defense systems. Although the …

Methicillin resistance and the biofilm phenotype in Staphylococcus aureus

H McCarthy, JK Rudkin, NS Black… - Frontiers in cellular …, 2015 - frontiersin.org
Antibiotic resistance and biofilm-forming capacity contribute to the success of
Staphylococcus aureus as a human pathogen in both healthcare and community settings …

Global epidemiology of community-associated methicillin resistant Staphylococcus aureus (CA-MRSA)

JR Mediavilla, L Chen, B Mathema… - Current opinion in …, 2012 - Elsevier
During the 1990s, various reports of community-associated methicillin-resistant
Staphylococcus aureus (CA-MRSA) infections appeared in the literature, caused by novel …

MRSA virulence and spread

M Otto - Cellular microbiology, 2012 - Wiley Online Library
Methicillin‐resistant S taphylococcus aureus (MRSA) is one of the most frequent causes of
hospital‐and community‐associated infections. Resistance to the entire class of β‐lactam …

Protein-based biofilm matrices in Staphylococci

P Speziale, G Pietrocola, TJ Foster… - Frontiers in cellular and …, 2014 - frontiersin.org
Staphylococcus aureus and Staphylococcus epidermidis are the most important etiological
agents of biofilm associated-infections on indwelling medical devices. Biofilm infections may …

MRSA lineage USA300 isolated from bloodstream infections exhibit altered virulence regulation

S Dyzenhaus, MJ Sullivan, B Alburquerque, D Boff… - Cell host & …, 2023 - cell.com
The epidemic community-associated methicillin-resistant Staphylococcus aureus (CA-
MRSA) USA300 lineage has recently become a leading cause of hospital-associated …

Staphylococcus aureus RNAIII and Its Regulon Link Quorum Sensing, Stress Responses, Metabolic Adaptation, and Regulation of Virulence Gene Expression

D Bronesky, Z Wu, S Marzi, P Walter… - Annual review of …, 2016 - annualreviews.org
Staphylococcus aureus RNAIII is one of the main intracellular effectors of the quorum-
sensing system. It is a multifunctional RNA that encodes a small peptide, and its noncoding …

Predicting the virulence of MRSA from its genome sequence

M Laabei, M Recker, JK Rudkin, M Aldeljawi… - Genome …, 2014 - genome.cshlp.org
Microbial virulence is a complex and often multifactorial phenotype, intricately linked to a
pathogen's evolutionary trajectory. Toxicity, the ability to destroy host cell membranes, and …