The application of clustered regularly interspaced short palindromic repeats (CRISPR) for
genetic manipulation has revolutionized life science over the past few years. CRISPR was …

Genome editing promises giant leaps forward in advancing biotechnology, agriculture, and
basic research. The process relies on the use of sequence specific nucleases (SSNs) to …

CRISPR/Cas, one of the most rapidly developing technologies in the world, has been
applied successfully in plant science. To test new nucleases, gRNA expression systems and …

Mutations with deleterious consequences in nature may be conditionally deleterious in crop
plants. That is, while some genetic variants may reduce fitness under wild conditions and be …

Soil contamination by toxic metals is a major health issue that could be partly solved by
using genetically-modified plants. For that, the recently developed technique of clustered …

Plants are exposed to a variety of abiotic and biotic stresses leading to increased formation
of reactive oxygen species (ROS) in plant cells. ROS are capable of oxidizing proteins …

There is a need to accelerate crop improvement by introducing alleles conferring host plant
resistance, abiotic stress adaptation, and high yield potential. Elite cultivars, landraces and …

Abstract Background The CRISPR-Cas9 system is a powerful and versatile tool for crop
genome editing. However, achieving highly efficient and specific editing in polyploid species …

Climate change, water scarcity, population growth, and food shortage are some of the
threatening challenges being faced in today's world. Among different types of stresses …

Due to an expanding world population and increased buying power, the demand for
ruminant products such as meat and milk is expected to grow substantially in coming years …