The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …

With antibiotic resistance on the rise, there is an urgent need for new antibacterial drugs and
products to treat or prevent infection. Many such products in current use, for example human …

Ulcerative colitis (UC) is a common chronic remitting disease driven through altered immune
responses with production of inflammatory cytokines. Oxidant/antioxidant balance is also …

Intestinal fibrosis is induced by excessive myofibroblast proliferation and collagen
deposition, which has been regarded as a general pathological feature in inflammatory …

Although antimicrobial peptides (AMPs) hold tremendous promise in overcoming the threats
of multidrug resistance, the main obstacle to successful therapeutic applications is their poor …

Chronic wounds are still regarded as a serious public health concern, which are on the
increase mainly due to the changes in life styles and aging of the human population. There …

Bacterial infection of wounds is a serious and growing issue and contributes to a delay in
wound healing. Whilst debridement is often the primary motivation for the clinical use of …

Antimicrobial peptides (AMPs) have a unique action mechanism that can help to solve
global problems in antibiotic resistance. However, their low therapeutic index and poor …

Lucilia sericata, the green bottle blowfly, has a long history of clinical use and an excellent
safety record which makes it safe for therapeutic clinical use. In regions where it is naturally …

Ovarian cancer is one of the most lethal gynecological malignancies, because of metastatic
dissemination with poor late clinical therapy. Maggots have been used in traditional Chinese …