[HTML][HTML] Tuberculosis IRIS: pathogenesis, presentation, and management across the spectrum of disease

CM Quinn, V Poplin, J Kasibante, K Yuquimpo… - Life, 2020 - mdpi.com
Antiretroviral therapy (ART), while essential in combatting tuberculosis (TB) and HIV
coinfection, is often complicated by the TB-associated immune reconstitution inflammatory …

[HTML][HTML] Calprotectin in lung diseases

OS Kotsiou, D Papagiannis, R Papadopoulou… - International journal of …, 2021 - mdpi.com
Calprotectin (CLP) is a heterodimer formed by two S-100 calcium-binding cytosolic proteins,
S100A8 and S100A9. It is a multifunctional protein expressed mainly by neutrophils and …

A host blood transcriptional signature differentiates multi-drug/rifampin-resistant tuberculosis (MDR/RR-TB) from drug susceptible tuberculosis: a pilot study

P Madamarandawala, S Rajapakse, B Gunasena… - Molecular biology …, 2023 - Springer
Background Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis is one
of the top thirteen causes of death worldwide. The major challenge to control TB is the …

[HTML][HTML] Tuberculosis-associated immune reconstitution inflammatory syndrome—an extempore game of misfiring with defense arsenals

R Vignesh, P Balakrishnan, HY Tan, YK Yong, V Velu… - Pathogens, 2023 - mdpi.com
The lethal combination involving TB and HIV, known as “syndemic” diseases, synergistically
act upon one another to magnify the disease burden. Individuals on anti-retroviral therapy …

[HTML][HTML] Natural killer repertoire restoration in TB/HIV co-infected individuals experienced an immune reconstitution syndrome (CAMELIA Trial, ANRS 12153)

P Pean, Y Madec, E Nerrienet, L Borand, D Laureillard… - Pathogens, 2023 - mdpi.com
IRIS is a common complication in HIV-infected patients treated for tuberculosis (TB) and
cART. Our aim was to evaluate NK cell reconstitution in HIV-infected patients with TB-IRIS …

[HTML][HTML] High levels of plasma S100A9 at admission indicate an increased risk of death in severe tuberculosis patients

Q Liu, R Li, Q Li, B Luo, J Lin, L Lyu - Journal of Clinical Tuberculosis and …, 2021 - Elsevier
Objective This study aims to evaluate plasma S100A9 levels in tuberculosis (TB) patients
with admission to the ICU as a marker to predict the risk of death for pulmonary severe TB …

[HTML][HTML] Expressions of interferon-stimulated genes in peripheral blood mononuclear cells from patients with secondary syphilis

Y Zhao, D Liu - Infection, Genetics and Evolution, 2021 - Elsevier
Background Syphilis is a sexually transmitted disease that threatens human health
worldwide. However, the immune regulation cascade caused by treponemia pallidum (TP) …

[PDF][PDF] Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome–An Extempore Game of Bursting Firecrackers with Defense Arsenals

R Vignesh, P Balakrishnan, HY Tan, YK Yong, V Velu… - 2023 - researchgate.net
The lethal combination involving TB and HIV, known as' syndemic'diseases synergistically
act upon one another to magnify the disease burden. Individuals on ART are at risk of …

Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome–An Extempore Game of Bursting Firecrackers with Defense Arsenals

V Ramachandran, P Balakrishnan, HY Tan, YK Yong… - 2023 - preprints.org
The lethal combination involving TB and HIV, known as' syndemic'diseases synergistically
act upon one another to magnify the disease burden. Individuals on ART are at risk of …

[PDF][PDF] Tuberculosis-Associ-ated Immune Reconstitution Inflam-matory Syndrome—An Extempore Game of Misfiring with Defense Ar-senals. Pathogens 2023, 12, 210

R Vignesh, P Balakrishnan, HY Tan, YK Yong, V Velu… - 2023 - researchgate.net
The lethal combination involving TB and HIV, known as “syndemic” diseases, synergistically
act upon one another to magnify the disease burden. Individuals on anti-retroviral therapy …