Microbial taxonomy in the era of OMICS: application of DNA sequences, computational tools and techniques

NK Mahato, V Gupta, P Singh, R Kumari… - Antonie Van …, 2017 - Springer
The current prokaryotic taxonomy classifies phenotypically and genotypically diverse
microorganisms using a polyphasic approach. With advances in the next-generation …

Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation

R Linares, CA Arnaud, G Effantin, C Darnault… - Science …, 2023 - science.org
Most bacteriophages present a tail allowing host recognition, cell wall perforation, and viral
DNA channeling from the capsid to the infected bacterium cytoplasm. The majority of tailed …

Phages infecting Faecalibacterium prausnitzii belong to novel viral genera that help to decipher intestinal viromes

JK Cornuault, MA Petit, M Mariadassou, L Benevides… - Microbiome, 2018 - Springer
Background Viral metagenomic studies have suggested a role for bacteriophages in
intestinal dysbiosis associated with several human diseases. However, interpretation of viral …

Virulent coliphages in 1-year-old children fecal samples are fewer, but more infectious than temperate coliphages

A Mathieu, M Dion, L Deng, D Tremblay… - Nature …, 2020 - nature.com
Bacteriophages constitute an important part of the human gut microbiota, but their impact on
this community is largely unknown. Here, we cultivate temperate phages produced by 900 E …

Strategies for developing phages into novel antimicrobial tailocins

C Woudstra, AN Sørensen, MCH Sørensen… - Trends in …, 2024 - cell.com
Tailocins are high-molecular-weight bacteriocins produced by bacteria to kill related
environmental competitors by binding and puncturing their target. Tailocins are promising …

Rates of Mutation and Recombination in Siphoviridae Phage Genome Evolution over Three Decades

A Kupczok, H Neve, KD Huang… - Molecular Biology …, 2018 - academic.oup.com
The evolution of asexual organisms is driven not only by the inheritance of genetic
modification but also by the acquisition of foreign DNA. The contribution of vertical and …

The enemy from within: a prophage of Roseburia intestinalis systematically turns lytic in the mouse gut, driving bacterial adaptation by CRISPR spacer acquisition

JK Cornuault, E Moncaut, V Loux, A Mathieu… - The ISME …, 2020 - academic.oup.com
Despite an overall temporal stability in time of the human gut microbiota at the phylum level,
strong variations in species abundance have been observed. We are far from a clear …

Dominant Vibrio cholerae phage exhibits lysis inhibition sensitive to disruption by a defensive phage satellite

SG Hays, KD Seed - elife, 2020 - elifesciences.org
Bacteria, bacteriophages that prey upon them, and mobile genetic elements (MGEs)
compete in dynamic environments, evolving strategies to sense the milieu. The first …

Genetic mining of newly isolated Salmophages for phage therapy

J Gendre, M Ansaldi, DR Olivenza, Y Denis… - International Journal of …, 2022 - mdpi.com
Salmonella enterica, a Gram-negative zoonotic bacterium, is mainly a food-borne pathogen
and the main cause of diarrhea in humans worldwide. The main reservoirs are found in …

Molecular mechanisms that contribute to horizontal transfer of plasmids by the bacteriophage SPP1

A Valero-Rello, M López-Sanz… - Frontiers in …, 2017 - frontiersin.org
Natural transformation and viral-mediated transduction are the main avenues of horizontal
gene transfer in Firmicutes. Bacillus subtilis SPP1 is a generalized transducing …