Glutamate receptor ion channels: structure, regulation, and function
The mammalian ionotropic glutamate receptor family encodes 18 gene products that
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …
Advances in epilepsy: mechanisms, clinical trials, and drug therapies
T Hu, J Zhang, J Wang, L Sha, Y Xia… - Journal of medicinal …, 2023 - ACS Publications
Epilepsy is a common disease of the nervous system characterized by transient brain
dysfunction caused by an abnormal electrical discharge from the brain neurons. The …
dysfunction caused by an abnormal electrical discharge from the brain neurons. The …
MicroRNA-128 governs neuronal excitability and motor behavior in mice
The control of motor behavior in animals and humans requires constant adaptation of
neuronal networks to signals of various types and strengths. We found that microRNA-128 …
neuronal networks to signals of various types and strengths. We found that microRNA-128 …
Hippocampal subregion-specific microRNA expression during epileptogenesis in experimental temporal lobe epilepsy
JA Gorter, A Iyer, I White, A Colzi, EA van Vliet… - Neurobiology of …, 2014 - Elsevier
Since aberrant miRNA expression has been implicated in numerous brain diseases, we
studied miRNA expression and miRNA regulation of important signaling pathways during …
studied miRNA expression and miRNA regulation of important signaling pathways during …
Genetic correction of SOD1 mutant iPSCs reveals ERK and JNK activated AP1 as a driver of neurodegeneration in amyotrophic lateral sclerosis
Although mutations in several genes with diverse functions have been known to cause
amyotrophic lateral sclerosis (ALS), it is unknown to what extent causal mutations impinge …
amyotrophic lateral sclerosis (ALS), it is unknown to what extent causal mutations impinge …
Plasma cytokines associated with febrile status epilepticus in children: a potential biomarker for acute hippocampal injury
WB Gallentine, S Shinnar, DC Hesdorffer, L Epstein… - …, 2017 - Wiley Online Library
Objective Our aim was to explore the association between plasma cytokines and febrile
status epilepticus (FSE) in children, as well as their potential as biomarkers of acute …
status epilepticus (FSE) in children, as well as their potential as biomarkers of acute …
Eph, a protein family coming of age: more confusion, insight, or complexity?
M Lackmann, AW Boyd - Science signaling, 2008 - science.org
Since the mid-1980s, Eph receptors have evolved from being regarded as orphan receptors
with unknown functions and ligands to becoming one of the most complex" global …
with unknown functions and ligands to becoming one of the most complex" global …
Mechanistic target of rapamycin complex 1 and 2 in human temporal lobe epilepsy
DM Talos, LM Jacobs, S Gourmaud… - Annals of …, 2018 - Wiley Online Library
Objective Temporal lobe epilepsy (TLE) is a chronic epilepsy syndrome defined by seizures
and progressive neurological disabilities, including cognitive impairments, anxiety, and …
and progressive neurological disabilities, including cognitive impairments, anxiety, and …
Histamine H3 receptor antagonists in relation to epilepsy and neurodegeneration: a systemic consideration of recent progress and perspectives
M Bhowmik, R Khanam… - British journal of …, 2012 - Wiley Online Library
The central histaminergic actions are mediated by H1, H2, H3 and H4 receptors. The
histamine H3 receptor regulates the release of histamine and a number of other …
histamine H3 receptor regulates the release of histamine and a number of other …
Expression and function of zinc-α2-glycoprotein
X Wei, X Liu, C Tan, L Mo, H Wang, X Peng, F Deng… - Neuroscience …, 2019 - Springer
Abstract Zinc-α2-glycoprotein (ZAG), encoded by the AZGP1 gene, is a major
histocompatibility complex I molecule and a lipid-mobilizing factor. ZAG has been …
histocompatibility complex I molecule and a lipid-mobilizing factor. ZAG has been …