Adequate oxygen supply is essential for the human brain to meet its high energy demands.
Therefore, elaborate molecular and systemic mechanism are in place to enable adaptation …

Most people spend the majority of their lives indoors. Research over the last thirty years has
focused on investigating the mechanisms through which specific elements of the built …

Rationale and objective In the United States, gun violence claims thousands of lives each
year and is a pressing public health issue. To gain a better understanding of this …

The cytoprotective transcriptor factor nuclear factor erythroid 2–related factor 2 (NRF2) is
part of a complex regulatory network that responds to environmental cues. To better …

Background: To date, the factors associated with the presence of depression or depressive
symptoms in the Peruvian population have not been described. This study aimed to …

Objective To develop clinically meaningful improvement thresholds in both the 17-item and
the 6-item Hamilton Rating Scale for Depression (HRSD) total scores in depressed …

Objectives The effects of altitude residence on ageing, longevity and mortality are poorly
understood. While adaptations to chronic exposure to altitude may exert beneficial effects on …

Depressed mood, which can occur in the context of major depressive disorder, bipolar
disorder, and other conditions, represents a serious threat to public health and wellness …

Suicide is the 10th leading cause of death in the United States. Although environment has
undeniable impact, evidence suggests that genetic factors play a significant role in …

Depression in children and adolescents has become a serious public health problem
worldwide. The objectives of this study were twofold: first, to investigate the status of …