Uterine fibroids
EA Stewart, SK Laughlin-Tommaso… - Nature reviews Disease …, 2016 - nature.com
Uterine fibroids (also known as leiomyomas or myomas) are common clonal neoplasms of
the uterus. Fibroids have both smooth muscle and fibroblast components, in addition to a …
the uterus. Fibroids have both smooth muscle and fibroblast components, in addition to a …
Uterine fibroids
SE Bulun - New England Journal of Medicine, 2013 - Mass Medical Soc
Uterine Fibroids | New England Journal of Medicine Skip to main content The New England
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …
Uterine fibroids: burden and unmet medical need
A Al-Hendy, ER Myers, E Stewart - Seminars in reproductive …, 2017 - thieme-connect.com
Uterine fibroids affect a wide cross-section of the population, with prevalence, symptom
severity, and overall disease burden generally higher among black women, likely due to …
severity, and overall disease burden generally higher among black women, likely due to …
Molecular and cellular insights into the development of uterine fibroids
Uterine leiomyomas represent the most common benign gynecologic tumor. These hormone-
dependent smooth-muscle formations occur with an estimated prevalence of~ 70% among …
dependent smooth-muscle formations occur with an estimated prevalence of~ 70% among …
Environmental factors, epigenetics, and developmental origin of reproductive disorders
Sex-specific differentiation, development, and function of the reproductive system are largely
dependent on steroid hormones. For this reason, developmental exposure to estrogenic and …
dependent on steroid hormones. For this reason, developmental exposure to estrogenic and …
Uterine leiomyoma: available medical treatments and new possible therapeutic options
Context: Uterine leiomyomas (fibroids or myomas) are benign tumors of the uterus and are
clinically apparent in up to 25% of reproductive-age women. Heavy or abnormal uterine …
clinically apparent in up to 25% of reproductive-age women. Heavy or abnormal uterine …
Genome-wide DNA methylation analysis predicts an epigenetic switch for GATA factor expression in endometriosis
MT Dyson, D Roqueiro, D Monsivais, CM Ercan… - PLoS …, 2014 - journals.plos.org
Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-
like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit …
like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit …
Genome-wide DNA methylation profiles in progression to in situand invasive carcinoma of the breast with impact on gene transcription and prognosis
Background Ductal carcinoma in situ (DCIS) of the breast is a precursor of invasive breast
carcinoma. DNA methylation alterations are thought to be an early event in progression of …
carcinoma. DNA methylation alterations are thought to be an early event in progression of …
[HTML][HTML] Complex networks of multiple factors in the pathogenesis of uterine leiomyoma
OBJECTIVE: To summarize the information regarding pathogenetic factors of leiomyoma
formation and growth, and to make a simple integrated pathogenetic view of this tumor for …
formation and growth, and to make a simple integrated pathogenetic view of this tumor for …
The mechanism and function of epigenetics in uterine leiomyoma development
Uterine leiomyomas, also known as uterine fibroids, are the most common pelvic tumors,
occurring in nearly 70% of all reproductive-aged women and are the leading indication for …
occurring in nearly 70% of all reproductive-aged women and are the leading indication for …