Glioblastoma Phagocytic Cell Death: Balancing the Opportunities for Therapeutic Manipulation
Macrophages and microglia are professional phagocytes that sense and migrate toward “eat-
me” signals. The role of phagocytic cells is to maintain homeostasis by engulfing senescent …
me” signals. The role of phagocytic cells is to maintain homeostasis by engulfing senescent …
[HTML][HTML] The Multifaced Role of Collagen in Cancer Development and Progression
GL Buglio, AL Cicero, S Campora… - International Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Collagen is a crucial protein in the extracellular matrix (ECM) essential for preserving tissue
architecture and supporting crucial cellular functions like proliferation and differentiation …
architecture and supporting crucial cellular functions like proliferation and differentiation …
Is modulation of immune checkpoints on glioblastoma-infiltrating myeloid cells a viable therapeutic strategy?
The field of immunology has traditionally focused on immune checkpoint modulation of
adaptive immune cells. However, many malignancies such as glioblastoma are mostly …
adaptive immune cells. However, many malignancies such as glioblastoma are mostly …
Glioma-associated tertiary lymphoid structures are sites of lymphocyte clonal expansion and plasma cell formation
P Cakmak, JH Lun, A Singh, J Macas, J Schupp… - bioRxiv, 2024 - biorxiv.org
Adult-type diffuse gliomas, the most common primary brain tumors, pose significant clinical
challenges due to limited treatment options, restricted anti-tumor immune response and …
challenges due to limited treatment options, restricted anti-tumor immune response and …
In vitro screening methods of novel immune checkpoint inhibitors related to T cell infiltration and anti-PD-1 resistance
Z He, X Zhou, Y Xiao, Y Gao - Methods in cell biology, 2024 - pubmed.ncbi.nlm.nih.gov
Immune checkpoint blockade-based cancer immunotherapy is an effective tool for cancer
treatment. PD-1/PD-L1 blockade, however, is limited by a low response rate and adaptive …
treatment. PD-1/PD-L1 blockade, however, is limited by a low response rate and adaptive …