Exploring the pivotal immunomodulatory and anti‐inflammatory potentials of glycyrrhizic and glycyrrhetinic acids
SA Richard - Mediators of Inflammation, 2021 - Wiley Online Library
Licorice extract is a Chinese herbal medication most often used as a demulcent or elixir. The
extract usually consists of many components but the key ingredients are glycyrrhizic (GL) …
extract usually consists of many components but the key ingredients are glycyrrhizic (GL) …
Natural products in licorice for the therapy of liver diseases: Progress and future opportunities
X Li, R Sun, R Liu - Pharmacological Research, 2019 - Elsevier
Liver diseases related complications represent a significant source of morbidity and mortality
worldwide, creating a substantial economic burden. Oxidative stress, excessive …
worldwide, creating a substantial economic burden. Oxidative stress, excessive …
Plant derived therapeutics for the treatment of Leishmaniasis
R Sen, M Chatterjee - Phytomedicine, 2011 - Elsevier
Diseases caused by insect borne trypanosomatid parasites are significant, yet remain a
neglected public health problem. Leishmania, a unicellular protozoan parasite is the …
neglected public health problem. Leishmania, a unicellular protozoan parasite is the …
The pathogenicity and virulence of Leishmania-interplay of virulence factors with host defenses
Leishmaniasis is a group of disease caused by the intracellular protozoan parasite of the
genus Leishmania. Infection by different species of Leishmania results in various host …
genus Leishmania. Infection by different species of Leishmania results in various host …
Carnosic acid modulates Akt/IKK/NF-κB signaling by PP2A and induces intrinsic and extrinsic pathway mediated apoptosis in human prostate carcinoma PC-3 cells
This study investigates the efficacy of carnosic acid (CA), a polyphenolic diterpene, isolated
from the plant rosemary (Rosemarinus officinalis), on androgen-independent human …
from the plant rosemary (Rosemarinus officinalis), on androgen-independent human …
A systematic review of pentacyclic triterpenes and their derivatives as chemotherapeutic agents against tropical parasitic diseases
Parasitic infections are among the leading global public health problems with very high
economic and mortality burdens. Unfortunately, the available treatment drugs are beset with …
economic and mortality burdens. Unfortunately, the available treatment drugs are beset with …
18β‐glycyrrhetinic acid induces apoptosis through modulation of Akt/FOXO3a/Bim pathway in human breast cancer MCF‐7 cells
Triterpenes found in plants display a multitude of biological activities, including anti‐tumor
properties. The present study investigates the effect of 18β‐glycyrrhetinic acid (GRA) a …
properties. The present study investigates the effect of 18β‐glycyrrhetinic acid (GRA) a …
Glycyrrhizic acid suppresses Cox-2-mediated anti-inflammatory responses during Leishmania donovani infection
S Bhattacharjee, A Bhattacharjee… - Journal of …, 2012 - academic.oup.com
Objectives The aim of the present study was to characterize glycyrrhizic acid (GA) and
assess its immunomodulatory potential in a model of experimental visceral leishmaniasis …
assess its immunomodulatory potential in a model of experimental visceral leishmaniasis …
Natural products: insights into leishmaniasis inflammatory response
IA Rodrigues, AM Mazotto, V Cardoso… - Mediators of …, 2015 - Wiley Online Library
Leishmaniasis is a vector‐borne disease that affects several populations worldwide, against
which there are no vaccines available and the chemotherapy is highly toxic. Depending on …
which there are no vaccines available and the chemotherapy is highly toxic. Depending on …
Function of macrophage and parasite phosphatases in leishmaniasis
The kinetoplastid protozoan parasites belonging to the genus Leishmania are the causative
agents of different clinical forms of leishmaniasis, a vector-borne infectious disease with …
agents of different clinical forms of leishmaniasis, a vector-borne infectious disease with …